221037

ENST00000399262, ENSP00000382204; ENSG00000171988

SEQUENCE   2540 AA;  284525 MW;  8B1727414D6B677F CRC64;
MAVETRAELV GKRFLCVAVG DEARSERWES GRGWRSWRAG VIRAVSHRDS RNPDLAVYVE
FDDLEWDKRE WVKVYEDFST FLVEYHLIWA KRNDPSQTQG SKSKQIQWPA LTFKPLVERN
IPSSVTAVEF LVDKQLDFLT EDSAFQPYQD DIDSLNPVLR DNPQLHEEVK VWVKEQKVQE
IFMQGPYSLN GYRVRVYRQD SATQWFTGII THHDLFTRTM IVMNDQVLEP QNVDPSMVQM
TFLDDVVHSL LKGENIGITS RRRSRANQNV NAVHSHYTRA QANSPRPAMN SQAAVPKQNT
HQQQQQRSIR PNKRKGSDSS IPDEEKMKEE KYDYISRGEN PKGKNKHLMN KRRKPEEDEK
KLNMKRLRTD NVSDFSESSD SENSNKRIID NSSEQKPENE LKNKNTSKIN GEEGKPHNNE
KAGEETLKNS QPPWDQIQED KKHEEAEKRK SVDTQLQEDM IIHSSEQSTV SDHNSNDLLP
QECNMDKTHT MELLPKEKFV SRPPTPKCVI DITNDTNLEK VAQENSSTFG LQTLQKMDPN
VSDSKHSIAN AKFLETAKKD SDQSWVSDVV KVDLTQSSVT NASSGNDHLN MEKEKYVSYI
SPLSAVSVME DKLHKRSPPP ETIKSKLNTS VDTHKIKSSP SPEVVKPKIT HSPDSVKSKA
TYVNSQATGE RRLANKIEHE LSRCSFHPIP TRSSTLETTK SPLIIDKNEH FTVYRDPALI
GSETGANHIS PFLSQHPFPL HSSSHRTCLN PGTHHPALTP APHLLAGSSS QTPLPTINTH
PLTSGPHHAV HHPHLLPTVL PGVPTASLLG GHPRLESAHA SSLSHLALAH QQQQQLLQHQ
SPHLLGQAHP SASYNQLGLY PIIWQYPNGT HAYSGLGLPS SKWVHPENAV NAEASLRRNS
PSPWLHQPTP VTSADGIGLL SHIPVRPSSA EPHRPLKITA HSSPPLTKTL VDHHKEELER
KAFMEPLRSV ASTSAKNDLD LNRSQTGKDC HLHRHFVDPV LNQLQRPPQE TGERLNKYKE
EHRRILQESI DVAPFTTKIK GLEGERENYS RVASSSSSPK SHIIKQDMDV ERSVSDLYKM
KHSVPQSLPQ SNYFTTLSNS VVNEPPRSYP SKEVSNIYGD KQSNALAAAA ANPQTLTSFI
TSLSKPPPLI KHQPESEGLV GKIPEHLPHQ IASHSVTTFR NDCRSPTHLT VSSTNTLRSM
PALHRAPVFH PPIHHSLERK EGSYSSLSPP TLTPVMPVNA GGKVQESQKP PTLIPEPKDS
QANFKSSSEQ SLTEMWRPNN NLSKEKTEWH VEKSSGKLQA AMASVIVRPS SSTKTDSMPA
MQLASKDRVS ERSSAGAHKT DCLKLAEAGE TGRIILPNVN SDSVHTKSEK NFQAVSQGSV
PSSVMSAVNT MCNTKTDVIT SAADTTSVSS WGGSEVISSL SNTILASTSS ECVSSKSVSQ
PVAQKQECKV STTAPVTLAS SKTGSVVQPS SGFSGTTDFI HLKKHKAALA AAQYKSSNAS
ETEPNAIKNQ TLSASLPLDS TVICSTINKA NSVGNGQASQ TSQPNYHTKL KKAWLTRHSE
EDKNTNKMEN SGNSVSEIIK PCSVNLIAST SSDIQNSVDS KIIVDKYVKD DKVNRRKAKR
TYESGSESGD SDESESKSEQ RTKRQPKPTY KKKQNDLQKR KGEIEEDLKP NGVLSRSAKE
RSKLKLQSNS NTGIPRSVLK DWRKVKKLKQ TGESFLQDDS CCEIGPNLQK CRECRLIRSK
KGEEPAHSPV FCRFYYFRRL SFSKNGVVRI DGFSSPDQYD DEAMSLWTHE NFEDDELDIE
TSKYILDIIG DKFCQLVTSE KTALSWVKKD AKIAWKRAVR GVREMCDACE ATLFNIHWVC
QKCGFVVCLD CYKAKERKSS RDKELYAWMK CVKGQPHDHK HLMPTQIIPG SVLTDLLDAM
HTLREKYGIK SHCHCTNKQN LQVGNFPTMN GVSQVLQNVL NHSNKISLCM PESQQQNTPP
KSEKNGGSSP ESDVGTDNKL TPPESQSPLH WLADLAEQKA REEKKENKEL TLENQIKEER
EQDNSESPNG RTSPLVSQNN EQGSTLRDLL TTTAGKLRVG STDAGIAFAP VYSMGAPSSK
SGRTMPNILD DIIASVVENK IPPSKTSKIN VKPELKEEPE ESIISAVDEN NKLYSDIPHS
WICEKHILWL KDYKNSSNWK LFKECWKQGQ PAVVSGVHKK MNISLWKAES ISLDFGDHQA
DLLNCKDSII SNANVKEFWD GFEEVSKRQK NKSGETVVLK LKDWPSGEDF KTMMPARYED
LLKSLPLPEY CNPEGKFNLA SHLPGFFVRP DLGPRLCSAY GVVAAKDHDI GTTNLHIEVS
DVVNILVYVG IAKGNGILSK AGILKKFEEE DLDDILRKRL KDSSEIPGAL WHIYAGKDVD
KIREFLQKIS KEQGLEVLPE HDPIRDQSWY VNKKLRQRLL EEYGVRTCTL IQFLGDAIVL
PAGALHQVQN FHSCIQVTED FVSPEHLVES FHLTQELRLL KEEINYDDKL QVKNILYHAV
KEMVRALKIH EDEVEDMEEN

• "The full-ORF clone resource of the German cDNA consortium.";,Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U.,Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H.,Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K.,Ottenwaelder B., Poustka A., Wiemann S., Schupp I.;,BMC Genomics 8:399-399(2007).,PubMeb:17974005 DOI:10.1186/1471-2164-8-399

• "The DNA sequence and comparative analysis of human chromosome 10.";,Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L.,Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K.,Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L.,Taylor A., Battles J., Bird C.P., Ainscough R., Almeida J.P.,Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J.,Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J.,Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D.,Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S.,Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L.,Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S.,Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L.,Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J.,Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M.,Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S.,Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M.,Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A.,Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T.,Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I.,Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T.,Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M.,Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W.,Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H.,Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L.,Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K.,Siebert R., Fechtel K., Bentley D., Durbin R.M., Hubbard T.,Doucette-Stamm L., Beck S., Smith D.R., Rogers J.;,Nature 429:375-381(2004).,PubMeb:15164054 DOI:10.1038/nature02462

• "Complete sequencing and characterization of 21,243 full-length humancDNAs.";,Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A.,Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M.,Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y.,Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M.,Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K.,Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S.,Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J.,Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y.,Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N.,Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S.,Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y.,Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T.,Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y.,Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S.,Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T.,Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M.,Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T.,Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K.,Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R.,Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.;,Nat. Genet. 36:40-45(2004).,PubMeb:14702039 DOI:10.1038/ng1285

• "Prediction of the coding sequences of unidentified human genes. XVI.The complete sequences of 150 new cDNA clones from brain which codefor large proteins in vitro.";,Nagase T., Kikuno R., Ishikawa K., Hirosawa M., Ohara O.;,DNA Res. 7:65-73(2000)., PubMeb:10718198 DOI:10.1093/dnares/7.1.65

• "Two classes of proteins dependent on either the presence or absenceof thyroid hormone for interaction with the thyroid hormonereceptor.";,Lee J.W., Choi H.-S., Gyuris J., Brent R., Moore D.D.;,Mol. Endocrinol. 9:243-254(1995)., PubMeb:7776974 DOI:10.1210/me.9.2.243

• "Identification and characterization of TRIP8 gene in silico.";,Katoh M., Katoh M.;,Int. J. Mol. Med. 12:817-821(2003).,PubMeb:14533015

• "ATM and ATR substrate analysis reveals extensive protein networksresponsive to DNA damage.";,Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R. III,Hurov K.E., Luo J., Bakalarski C.E., Zhao Z., Solimini N.,Lerenthal Y., Shiloh Y., Gygi S.P., Elledge S.J.;,Science 316:1160-1166(2007).,PubMeb:17525332 DOI:10.1126/science.1140321

• "A quantitative atlas of mitotic phosphorylation.";,Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.;,Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).,PubMeb:18669648 DOI:10.1073/pnas.0805139105

• "Lysine acetylation targets protein complexes and co-regulates majorcellular functions.";,Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.,Olsen J.V., Mann M.;,Science 325:834-840(2009).,PubMeb:19608861 DOI:10.1126/science.1175371