Feature key |
Position(s) |
Length |
Description |
Polypeptide chain |
1 - 1090 |
1090 |
Neurofilament heavy polypeptide. /FTId=PRO_0000063801. |
Internal sequence repetition |
522 - 527 |
6 |
1. |
Internal sequence repetition |
528 - 533 |
6 |
2. |
Internal sequence repetition |
534 - 539 |
6 |
3. |
Internal sequence repetition |
540 - 545 |
6 |
4. |
Internal sequence repetition |
546 - 551 |
6 |
5. |
Internal sequence repetition |
552 - 557 |
6 |
6. |
Internal sequence repetition |
558 - 563 |
6 |
7. |
Internal sequence repetition |
564 - 569 |
6 |
8. |
Internal sequence repetition |
570 - 575 |
6 |
9. |
Internal sequence repetition |
576 - 581 |
6 |
10. |
Internal sequence repetition |
582 - 587 |
6 |
11. |
Internal sequence repetition |
588 - 593 |
6 |
12. |
Internal sequence repetition |
594 - 599 |
6 |
13. |
Internal sequence repetition |
600 - 605 |
6 |
14. |
Internal sequence repetition |
606 - 611 |
6 |
15. |
Internal sequence repetition |
612 - 617 |
6 |
16. |
Internal sequence repetition |
618 - 623 |
6 |
17. |
Internal sequence repetition |
624 - 629 |
6 |
18. |
Internal sequence repetition |
630 - 635 |
6 |
19. |
Internal sequence repetition |
636 - 641 |
6 |
20. |
Internal sequence repetition |
642 - 647 |
6 |
21. |
Internal sequence repetition |
648 - 653 |
6 |
22. |
Internal sequence repetition |
654 - 659 |
6 |
23. |
Internal sequence repetition |
660 - 665 |
6 |
24. |
Internal sequence repetition |
666 - 671 |
6 |
25. |
Internal sequence repetition |
672 - 677 |
6 |
26. |
Internal sequence repetition |
678 - 683 |
6 |
27. |
Internal sequence repetition |
684 - 689 |
6 |
28. |
Internal sequence repetition |
690 - 695 |
6 |
29. |
Internal sequence repetition |
696 - 701 |
6 |
30. |
Internal sequence repetition |
702 - 707 |
6 |
31. |
Internal sequence repetition |
708 - 713 |
6 |
32. |
Internal sequence repetition |
714 - 719 |
6 |
33. |
Internal sequence repetition |
720 - 725 |
6 |
34. |
Internal sequence repetition |
726 - 731 |
6 |
35. |
Internal sequence repetition |
732 - 737 |
6 |
36. |
Internal sequence repetition |
738 - 743 |
6 |
37. |
Internal sequence repetition |
744 - 749 |
6 |
38. |
Internal sequence repetition |
750 - 755 |
6 |
39. |
Internal sequence repetition |
756 - 761 |
6 |
40. |
Internal sequence repetition |
762 - 767 |
6 |
41. |
Internal sequence repetition |
768 - 773 |
6 |
42. |
Internal sequence repetition |
774 - 779 |
6 |
43; approximate. |
Internal sequence repetition |
782 - 787 |
6 |
44. |
Internal sequence repetition |
788 - 793 |
6 |
45. |
Internal sequence repetition |
794 - 799 |
6 |
46. |
Internal sequence repetition |
808 - 813 |
6 |
47. |
Internal sequence repetition |
814 - 819 |
6 |
48. |
Internal sequence repetition |
833 - 838 |
6 |
49. |
Internal sequence repetition |
858 - 863 |
6 |
50. |
Internal sequence repetition |
866 - 871 |
6 |
51. |
Internal sequence repetition |
887 - 892 |
6 |
52. |
Region |
2 - 98 |
97 |
Head. |
Region |
99 - 411 |
313 |
Rod. |
Region |
99 - 130 |
32 |
Coil 1A. |
Region |
131 - 143 |
13 |
Linker 1. |
Region |
144 - 242 |
99 |
Coil 1B. |
Region |
243 - 264 |
22 |
Linker 12. |
Region |
265 - 286 |
22 |
Coil 2A. |
Region |
287 - 290 |
4 |
Linker 2. |
Region |
291 - 411 |
121 |
Coil 2B. |
Region |
412 - 1090 |
679 |
Tail. |
Region |
522 - 892 |
371 |
52 X 6 AA approximate tandem repeats of |
Compositionally biased region |
439 - 520 |
82 |
Glu-rich (acidic). |
Compositionally biased region |
890 - 1090 |
201 |
Glu/Lys-rich. |
Posttranslational modification of a residue |
61 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
416 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
499 |
1 |
Phosphothreonine. |
Posttranslational modification of a residue |
500 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
523 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
529 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
535 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
541 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
547 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
553 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
559 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
565 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
571 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
577 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
583 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
613 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
619 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
625 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
631 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
637 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
649 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
655 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
661 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
667 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
673 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
679 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
685 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
691 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
697 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
703 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
709 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
715 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
721 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
727 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
733 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
739 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
745 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
751 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
757 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
763 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
769 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
775 |
1 |
Phosphothreonine. |
Posttranslational modification of a residue |
783 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
789 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
815 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
834 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
839 |
1 |
Phosphothreonine. |
Posttranslational modification of a residue |
867 |
1 |
Phosphoserine. |
Posttranslational modification of a residue |
888 |
1 |
Phosphoserine. |
Different sources report differing sequences |
134 - 135 |
2 |
QA -> K (in Ref. 2; AAA39813). |
Different sources report differing sequences |
202 |
1 |
Missing (in Ref. 2; AAA39813). |
Different sources report differing sequences |
284 |
1 |
T -> S (in Ref. 2; AAA39813). |
Different sources report differing sequences |
495 |
1 |
G -> L (in Ref. 2; AAA39813). |
Different sources report differing sequences |
519 |
1 |
E -> EEAKSPG (in Ref. 1; AAA39809 and 3; |
Different sources report differing sequences |
549 |
1 |
G -> R (in Ref. 1; AAA39809 and 3; |
Different sources report differing sequences |
694 - 717 |
24 |
Missing (in Ref. 1; AAA39809 and 3; |
Different sources report differing sequences |
817 |
1 |
V -> M (in Ref. 1; AAA39809, 3; CAA83229 |
Different sources report differing sequences |
846 - 847 |
2 |
KH -> ND (in Ref. 1; AAA39809, 3; |
Different sources report differing sequences |
846 - 847 |
2 |
KH -> TV (in Ref. 2; AAA39813). |