7294

ENST00000264316, ENSP00000264316; ENSG00000074966

SEQUENCE   527 AA;  61258 MW;  BCCA081F4155CAA6 CRC64;
MILSSYNTIQ SVFCCCCCCS VQKRQMRTQI SLSTDEELPE KYTQRRRPWL SQLSNKKQSN
TGRVQPSKRK PLPPLPPSEV AEEKIQVKAL YDFLPREPCN LALRRAEEYL ILEKYNPHWW
KARDRLGNEG LIPSNYVTEN KITNLEIYEW YHRNITRNQA EHLLRQESKE GAFIVRDSRH
LGSYTISVFM GARRSTEAAI KHYQIKKNDS GQWYVAERHA FQSIPELIWY HQHNAAGLMT
RLRYPVGLMG SCLPATAGFS YEKWEIDPSE LAFIKEIGSG QFGVVHLGEW RSHIQVAIKA
INEGSMSEED FIEEAKVMMK LSHSKLVQLY GVCIQRKPLY IVTEFMENGC LLNYLRENKG
KLRKEMLLSV CQDICEGMEY LERNGYIHRD LAARNCLVSS TCIVKISDFG MTRYVLDDEY
VSSFGAKFPI KWSPPEVFLF NKYSSKSDVW SFGVLMWEVF TEGKMPFENK SNLQVVEAIS
EGFRLYRPHL APMSIYEVMY SCWHEKPEGR PTFAELLRAV TEIAETW

• "TXK, a novel human tyrosine kinase expressed in T cells sharessequence identity with Tec family kinases and maps to 4p12.";,Haire R.N., Ohta Y., Lewis J.E., Fu S.M., Kroisel P.M., Litman G.W.;,Hum. Mol. Genet. 3:897-901(1994)., PubMeb:7951233 DOI:10.1093/hmg/3.6.897

• "Human Txk: genomic organization, structure and contiguous physicallinkage with the Tec gene.";,Ohta Y., Haire R.N., Amemiya C.T., Litman R.T., Trager T., Riess O.,Litman G.W.;,Oncogene 12:937-942(1996)., PubMeb:8632917

• "Solution structure of the SH2 domain of human tyrosine-protein kinaseTXK.";,Submitted (OCT-2006) to the PDB data bank.

• "Patterns of somatic mutation in human cancer genomes.";,Greenman C., Stephens P., Smith R., Dalgliesh G.L., Hunter C.,Bignell G., Davies H., Teague J., Butler A., Stevens C., Edkins S.,O'Meara S., Vastrik I., Schmidt E.E., Avis T., Barthorpe S.,Bhamra G., Buck G., Choudhury B., Clements J., Cole J., Dicks E.,Forbes S., Gray K., Halliday K., Harrison R., Hills K., Hinton J.,Jenkinson A., Jones D., Menzies A., Mironenko T., Perry J., Raine K.,Richardson D., Shepherd R., Small A., Tofts C., Varian J., Webb T.,West S., Widaa S., Yates A., Cahill D.P., Louis D.N., Goldstraw P.,Nicholson A.G., Brasseur F., Looijenga L., Weber B.L., Chiew Y.-E.,DeFazio A., Greaves M.F., Green A.R., Campbell P., Birney E.,Easton D.F., Chenevix-Trench G., Tan M.-H., Khoo S.K., Teh B.T.,Yuen S.T., Leung S.Y., Wooster R., Futreal P.A., Stratton M.R.;,Nature 446:153-158(2007).,PubMeb:17344846 DOI:10.1038/nature05610