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Catalog Products » Recombinant Proteins » Growth Factors » Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF), Mouse

GM-CSF, Mouse

Synonyms Granulocyte/Macrophage-Colony Stimulating Factor, GMCSF
Description Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts) in response to cytokine or immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, GM-CSF is also a growth factor for erythroid, megakaryocyte and eosinophil progenitors. On mature hematopoietic cells, GM-CSF is a survival factor for and activates the effectors functions of granulocytes, monocytes/macrophages and eosinophils.
Species Mouse
Source CHO
Biological Activity ED50 < 0.05 ng/ml, measured in a cell proliferation assay using mouse FDC-P1 cells, corresponding to a specific activity of >2 x 107 units/mg.
Sequence
APTRSPITVT RPWKHVEAIK EALNLLDDMP VTLNEEVEVV
SNEFSFKKLT CVQTRLKIFE QGLRGNFTKL KGALNMTASY
YQTYCPPTPE TDCETQVTTY ADFIDSLKTF LTDIPFECKK
PVQK

Measured Molecular Weight 15~19 kDa, observed by non-reducing SDS-PAGE.
Purity > 95% as analyzed by SDS-PAGE and HPLC.
Formulation Lyophilized after extensive dialysis against PBS.
Reconstitution Reconstituted in ddH2O or PBS at 100 μg/ml.
Endotoxin Level <0.2 EU/μg, determined by LAL method.
Storage Lyophilized recombinant murine Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, rmGM-CSF should be stable up to 1 week at 4°C or up to 2 months at -20°C.
Note For research use only




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Cat. No. Z02979
Size
Price
10 ug $85.00
50 ug $275.00
1 mg $2100.00