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Catalog Products » Recombinant Proteins » Growth Factors » Granulocyte Colony Stimulating Factor (G-CSF), Human(CHO-expressed)

G-CSF, Human(CHO-expressed)

Synonyms Granulocyte Colony-Stimulating Factor, CSF-3, MGI-1G, GM-CSF beta, pluripoietin.
Description Human Granulocyte Colony Stimulating Factor (G-CSF) contains internal disulfide bonds. Among the family of colony-stimulating factors, Granulocyte Colony Stimulating Factor (G-CSF) is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines. The synthesis of Granulocyte Colony Stimulating Factor (G-CSF) can be induced by bacterial endotoxins, TNF, Interleukin-1 and GM-CSF. Prostaglandin E2 inhibits the synthesis of Granulocyte Colony Stimulating Factor (G-CSF). In epithelial, endothelial, and fibroblastic cells, the secretion of Granulocyte Colony Stimulating Factor (G-CSF) is induced by Interleukin-17.
Species Human
Source CHO
Biological Activity ED50< 0.1 ng/ml, determined by the dose-dependent stimulation of the proliferation of murine M-NFS-60 cells, corresponding to a specific activity of >1 x 107 units/mg.
Sequence
TPLGPASSLP QSFLLKCLEQ VRKIQGDGAA LQEKLCATYK
LCHPEELVLL GHSLGIPWAP LSSCPSQALQ LAGCLSQLHS
GLFLYQGLLQ ALEGISPELG PTLDTLQLDV ADFATTIWQQ
MEELGMAPAL QPTQGAMPAF ASAFQRRAGG VLVASHLQSF
LEVSYRVLRH LAQP

Measured Molecular Weight 18.7kDa, observed by non-reducing SDS-PAGE.
Purity > 95% as analyzed by SDS-PAGE and HPLC.
Formulation Lyophilized after extensive dialysis against PBS.
Reconstitution Reconstituted in ddH2O or PBS at 100 μg/ml.
Endotoxin Level <0.2 EU/μg, determined by LAL method.
Storage Lyophilized recombinant human Granulocyte Colony Stimulating Factor (G-CSF) remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, rhG-CSF should be stable up to 1 week at 4°C or up to 2 months at -20°C.
Note For research use only

  • G-CSF, Human(CHO-expressed)
  • G-CSF, Human(CHO-expressed)

    ED₅₀< 0.1 ng/ml, determined by the dose-dependent stimulation of the proliferation of murine M-NFS-60 cells, corresponding to a specific activity of >1 x 10⁷ units/mg.




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Cat. No. Z02980
Size
Price
10 ug $85.00
50 ug $275.00
1 mg $2100.00