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Catalog Products » Recombinant Proteins » Growth Factors » Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF), Human(CHO-expressed)

GM-CSF, Human(CHO-expressed)

GM-CSF, Human(CHO-expressed)

ED₅₀< 0.2 ng/ml, measured in a cell proliferation assay using TF-1 cells, corresponding to a specific activity of > 5×10⁶ units/mg.

GM-CSF, Human(CHO-expressed)

GenScript product showed equal activity compared to competitor P

Synonyms Granulocyte/Macrophage Colony-Stimulating Factor, CSF-2, MGI-1GM, pluripoietin-α
Description Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) is produced by a number of different cell types, including activated T cells, B cells, macrophages, mast cells, endothelial cells, and fibroblasts, in response to cytokine of immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) is a growth factor for erythroid, megakaryocyte, and eosinophil progenitors. On mature hematopoietic cells, GM-CSF is a survival factor for and activates the effectors functions of granulocytes,monocytes/macrophages and eosinophils.
Human Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) can induce human endothelial cells to migrate and proliferate. Additionally, Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) can stimulate the proliferation of a number of tumor cell lines, including osteogenic sarcoma, carcinoma, and adenocarcinoma cell lines.
Species Human
Source CHO
Biological Activity ED50 < 0.2 ng/ml, measured in a cell proliferation assay using TF-1 cells, corresponding to a specific activity of > 5×106 units/mg.
Sequence
APARSPSPST QPWEHVNAIQ EARRLLNLSR DTAAEMNETV
EVISEMFDLQ EPTCLQTRLE LYKQGLRGSL TKLKGPLTMM
ASHYKQHCPP TPETSCATQI ITFESFKENL KDFLLVIPFD
CWEPVQE

Measured Molecular Weight 22-28 kDa, observed by non-reducing SDS-PAGE.
Purity > 95% as analyzed by SDS-PAGE and HPLC.
Formulation Lyophilized after extensive dialysis against PBS.
Reconstitution Reconstituted in ddH2O or PBS at 100 μg/ml.
Endotoxin Level < 0.2 EU/μg, determined by LAL method.
Storage Lyophilized recombinant human Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, rhGM-CSF should be stable up to 1 week at 4°C or up to 2 months at -20°C.
Note For research use only

  • GM-CSF, Human(CHO-expressed)
  • GM-CSF, Human(CHO-expressed)

    ED₅₀< 0.2 ng/ml, measured in a cell proliferation assay using TF-1 cells, corresponding to a specific activity of > 5×10⁶ units/mg.

  • GM-CSF, Human(CHO-expressed)
  • GM-CSF, Human(CHO-expressed)

    GenScript product showed equal activity compared to competitor P




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Cat. No. Z02983
Size
Price
10 ug $85.00
50 ug $275.00
1 mg $2100.00