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Catalog Products » Recombinant Proteins » Growth Factors » Granulocyte Macrophage Colony Stimulating Factor (GM-CSF), Rat

GM-CSF, Rat

Synonyms Granulocyte/Macrophage Colony-Stimulating Factor, CSF-2, MGI-1GM, pluripoietin-alpha
Description Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) is produced by a number of different cell types, including activated T cells, B cells, macrophages, mast cells, endothelial cells, and fibroblasts, in response to cytokine of immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) is a growth factor for erythroid, megakaryocyte, and eosinophil progenitors. On mature hematopoietic, monocytes/macrophages and eosinophils.
Species Rat
Source CHO
Biological Activity ED50 < 5 pg/ml, measured in a cell proliferation assay using FDC-P1 cells, corresponding to a specific activity of > 2×108 units/mg.
Sequence
APTRSPNPVT RPWKHVDAIK EALSLLNDMR ALENEKNEDV
DIISNEFSIQ RPTCVQTRLK LYKQGLRGNL TKLNGALTMI
ASHYQTNCPP TPETDCEIEV TTFEDFIKNL KGFLFDIPFD
CWKPVQK

Measured Molecular Weight 16-26 kDa, observed by non-reducing SDS-PAGE.
Purity > 95% as analyzed by SDS-PAGE and HPLC.
Formulation Lyophilized after extensive dialysis against PBS.
Reconstitution Reconstituted in ddH2O or PBS at 100 μg/ml.
Endotoxin Level < 0.2 EU/μg, determined by LAL method.
Storage Lyophilized recombinant Rat Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, rrGM-CSF should be stable up to 1 week at 4°C or up to 2 months at -20°C.
Note For research use only


Jin C., et al. HV1 Acts as a Sodium Sensor and Promotes Superoxide Production in Medullary Thick Ascending Limb of Dahl Salt-Sensitive Rats. Hypertension. 2014June

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Cat. No. Z02992
Size
Price
10 ug $65.00
50 ug $159.00
1 mg $1500.00