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Catalog Products » Recombinant Proteins » Cytokines » Interleukin-5 (IL-5), Mouse

IL-5, Mouse

Synonyms EDF,BCDFII,TRF
Description Interleukin-5 (rmIL-5),produced by mast cells, T cells and eosinophils, is responsible for the activities attributed to eosinophil differentiating factor, B cell growth factor II and T cell-replacing factor (TRF). It can increase production and mobilization of eosinophils and CD34+ progenitors from the bone marrow. IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. IL-5 also promotes differentiation of basophils and primes them for histamine and leukotriene release.

Recombinant mouse Interleukin-5 (rmIL-5) produced in E.coli is a disulfide-linked homodimer containing two non-glycosylated polypeptide chains of 113 amino acids each. A fully biologically active molecule, rmIL-5 has a molecular mass of 26.2kDa analyzed by non-reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.
Species Mouse
Source E. coli
Biological Activity ED50 < 2.0 ng/ml, measured by a cell proliferation assay using TF-1 Cells, corresponding to a specific activity of > 5.0× 105 units/mg.
Sequence
MEIPMSTVVK ETLTQLSAHR ALLTSNETMR LPVPTHKNHQ
LCIGEIFQGL DILKNQTVRG GTVEMLFQNL SLIKKYIDRQ
KEKCGEERRR TRQFLDYLQE FLGVMSTEWA MEG

Measured Molecular Weight 26.2kDa, observed by non-reducing SDS-PAGE.
Purity > 95% by SDS-PAGE and HPLC analyses.
Formulation Lyophilized after extensive dialysis against PBS.
Reconstitution Reconstituted in ddH2O at 100 μg/ml.
Endotoxin Level < 0.2 EU/μg, determined by LAL method.
Storage Lyophilized recombinant mouse Interleukin-5 (rmIL-5) remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, rmIL-5 should be stable up to 2 weeks at 4°C or up to 3 months at -20°C.
Note For research use only

  • IL-5, Mouse
  • IL-5, Mouse

    ED₅₀< 2.0 ng/ml, measured by a cell proliferation assay using TF-1 Cells, corresponding to a specific activity of > 5.0× 10⁵units/mg.




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Cat. No. Z02998
Size
Price
500 ug $675.00
50 ug $195.00
10 ug $85.00