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Catalog Products » Recombinant Proteins » Growth Factors » Vascular Endothelial Growth Factor 165 (VEGF165), Rat (CHO-expressed)

VEGF165, Rat (CHO-expressed)

Synonyms Vascular Endothelial Growth Factor, VPF, Folliculostellate cell-derived growth factor, Glioma-derived endothelial cell mitogen
Description Vascular Endothelial Growth Factor (VEGF) is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, Vascular Endothelial Growth Factor (VEGF) plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates Vascular Endothelial Growth Factor (VEGF) in the induction of tumor metastasis and intra-ocular neovascular syndromes. Vascular Endothelial Growth Factor (VEGF) signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product.
Species Rat
Source CHO
Biological Activity ED50 < 4 ng/ml, measured in a cell proliferation assay using HUVEC cells, corresponding to a specific activity of >2.5 x 105 units/mg
Sequence
APTTEGEQKA HEVVKFMDVY QRSYCRPIET LVDIFQEYPD
EIEYIFKPSC VPLMRCAGCC NDEALECVPT SESNVTMQIM
RIKPHQSQHI GEMSFLQHSR CECRPKKDRT KPENHCEPCS
ERRKHLFVQD PQTCKCSCKN TDSRCKARQL ELNERTCRCD
KPRR

Measured Molecular Weight 35-48 kDa, observed by non-reducing SDS-PAGE.
Purity > 95% as analyzed by SDS-PAGE and HPLC.
Formulation Lyophilized after extensive dialysis against PBS.
Reconstitution Reconstituted in ddH2O or PBS at 100 μg/ml.
Endotoxin Level < 0.2 EU/μg, determined by LAL method.
Storage Lyophilized recombinant Rat Vascular Endothelial Growth Factor 165 (VEGF165) remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, rrVEGF165 should be stable up to 1 week at 4°C or up to 2 months at -20°C.
Note For research use only

  • VEGF165, Rat (CHO-expressed)
  • VEGF165, Rat (CHO-expressed)

    ED₅₀< 4 ng/ml, measured in a cell proliferation assay using HUVEC cells, corresponding to a specific activity of >2.5 x 10⁵ units/mg




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Cat. No. Z03006
Size
Price
10 ug $85.00
50 ug $195.00
1 mg $1500.00