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Catalog Products » Recombinant Proteins » Cytokines » Interleukin-9 (IL-9), Human

IL-9, Human

Synonyms p40 cytokine, T-cell growth factor p40
Description Interleukin 9, also known as IL9, is a cytokine (cell signalling molecule) belonging to the group of interleukins. The protein encoded by this gene is a cytokine produced by T-cells and specifically by CD4+ helper cells that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin-9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness.
Species Human
Source CHO
Biological Activity ED50 < 1 ng/ml, measured in a cell proliferation assay using MO7e cells, corresponding to a specific activity of > 1×106 units/mg.
Sequence
QGCPTLAGIL DINFLINKMQ EDPASKCHCS ANVTSCLCLG
IPSDNCTRPC FSERLSQMTN TTMQTRYPLI FSRVKKSVEV
LKNNKCPYFS CEQPCNQTTA GNALTFLKSL LEIFQKEKMR
GMRGKI

Measured Molecular Weight 25-40 kDa, observed by non-reducing SDS-PAGE.
Purity > 95% as analyzed by SDS-PAGE and HPLC.
Formulation Lyophilized after extensive dialysis against PBS.
Reconstitution Reconstituted in ddH2O or PBS at 100 μg/ml.
Endotoxin Level < 0.2 EU/μg, determined by LAL method.
Storage Lyophilized recombinant human Interlerkin 9 (IL-9) remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, rhIL-9 should be stable up to 1 week at 4°C or up to 2 months at -20°C.
Note For research use only

  • IL-9, Human
  • IL-9, Human

    ED₅₀< 1 ng/ml, measured in a cell proliferation assay using MO7e cells, corresponding to a specific activity of > 1×10⁶ units/mg.




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Cat. No. Z03013
Size
Price
50 ug $275.00
10 ug $85.00
1 mg $2100.00