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Catalog Products » Recombinant Proteins » Growth Factors » Fibroblast Growth Factor-basic (FGF-basic), Mouse

FGF-basic, Mouse

Synonyms Fibroblast Growth Factor-basic, FGF-2, HBGF-2, Prostatropin; BFGF; FGFB;
Description Fibroblast Growth Factor-basic (FGF-basic), also known as HBGF-2, is a non-glycosylated heparin-binding growth factor that belongs to the FGF family. FGF-basic is present in basement membranes and in the subendothelial extracellular matrix of blood vessels. FGF-basic signals through FGFR1, 2, 3 and 4 that plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration.
Recombinant mouse Fibroblast Growth Factor-basic (rmFGF-basic) produced in E. coli is a single non-glycosylated polypeptide chain containing 146 amino acids. A fully biologically active molecule, rmFGF-basic has a molecular mass of 16.4 kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.
Accession No P15655
Species Mouse
Source E. coli
Biological Activity ED50 < 0.5 ng/ml, measured by a cell proliferation assay using 3T3 Cells, corresponding to a specific activity of > 2.0× 106 units/mg.
Sequence
MPALPEDGGA AFPPGHFKDP KRLYCKNGGF FLRIHPDGRV
DGVREKSDPH VKLQLQAEER GVVSIKGVCA NRYLAMKEDG
RLLASKCVTE ECFFFERLES NNYNTYRSRK YSSWYVALKR
TGQYKLGSKT GPGQKAILFL PMSAKS

Measured Molecular Weight 16.4 kDa, observed by reducing SDS-PAGE.
Purity > 95% by SDS-PAGE and HPLC analyses.
Formulation Lyophilized after extensive dialysis against PBS.
Reconstitution Reconstituted in ddH2O at 100 μg/ml.
Endotoxin Level < 0.2 EU/μg, determined by LAL method.
Storage Lyophilized recombinant mouse Fibroblast Growth Factor-basic (rmFGF-basic) remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, rmFGF-basic should be stable up to 2 weeks at 4°C or up to 3 months at -20°C.
Note For research use only


Cat. No.
Product Name
Price
Z03310-10
FGF-basic (145aa), Human - 10 ug
$40.00
Z03166-10
FGF-basic (146aa), Human - 10 ug
$39.00
Z03116-10
FGF-basic (154aa), Human - 10 ug
$40.00
Z03230-10
FGF-basic, Bovine - 10 ug
$40.00
Z02786-50
FGF-basic, Rat - 50 ug
$159.00
Z03193-10
FGF-basic, Rat - 10 ug
$40.00
 



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Cat. No. Z03016
Size
Price
10 ug $40.00
50 ug $85.00
1 mg $625.00