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Catalog Products » Recombinant Proteins » Cytokines » Interleukin-13 (IL-13), Human(CHO-expressed)

IL-13, Human(CHO-expressed)

Synonyms NC30 (Human), P600 (Murine);IL-13 (human)
Description Interleukin 13 (IL-13) is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1beta, TNF-alpha, IL-6 and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching resulting in increased production of IgE. Blocking of IL-13 activity inhibits the pathophysiology of asthma. Human and mouse IL-13 is cross-species reactive.
Recombinant human interleukin 13 expressed in CHO cells is glycosylated protein with molecular weight range from 25 to 45 kDa shown in non-reducing SDS-PAGE.
Accession No P35225
Species Human
Source CHO
Biological Activity ED50 < 15 ng/ml, measured in a cell proliferation assay using TF-1 cells, corresponding to a specific activity of > 6.7×105 units/mg.

Measured Molecular Weight 25-45 kDa, observed by non-reducing SDS-PAGE.
Purity > 95% as analyzed by SDS-PAGE.
Formulation Lyophilized after extensive dialysis against PBS.
Reconstitution Reconstituted in ddH2O or PBS at 100 μg/ml.
Endotoxin Level < 0.2 EU/μg, determined by LAL method.
Storage Lyophilized recombinant human Interleukin 13 (IL-13) remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, rhIL-13 should be stable up to 1 week at 4°C or up to 2 months at -20°C.
Note For research use only

  • IL-13, Human(CHO-expressed)
  • IL-13, Human(CHO-expressed)

    ED₅₀< 15 ng/ml, measured in a cell proliferation assay using TF-1 cells, corresponding to a specific activity of > 6.7×10⁵ units/mg.

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Cat. No. Z03020
50 ug $275.00
10 ug $85.00
1 mg $2100.00