Adiponectin/Acrp30, Human
| Synonyms | Arcp-30, GBP-28, Apm-1 |
| Description | Adipolean/gArcp30 is produced and secreted exclusively by adipocytes, and is a relatively abundant plasma protein, accounting for up to 0.05% of total serum protein. It is an adipocytederived protein with wide ranging paracrine and endocrine effects on metabolism and inflammation. It is induced during adipocyte differentiation, and its secretion is stimulated by insulin. It promotes adipocyte differentiation, fatty acid catabolism, and insulin sensitivity and is negatively correlated with obesity, type 2 diabetes, and atherogenesis. |
| Accession No | Q15848 |
| Species | Human |
| Source | HEK 293 |
| Biological Activity | ED50 < 2 μg/ml, measured in a cell proliferation assay using M1 cells. |
| Sequence | KGEPGEGAYV YRSAFSVGLE TYVTIPNMPI RFTKIFYNQQ NHYDGSTGKF HCNIPGLYYF AYHITVYMKD VKVSLFKKDK AMLFTYDQYQ ENNVDQASGS VLLHLEVGDQ VWLQVYGEGE RNGLYADNDN DSTFTGFLLY HDTN |
| Measured Molecular Weight | 16~17 kDa, observed by reducing SDS-PAGE. |
| Purity | > 95% as analyzed by SDS-PAGE. |
| Formulation | Lyophilized after extensive dialysis against PBS. |
| Reconstitution | Reconstituted in ddH2O or PBS at 100 μg/ml. |
| Endotoxin Level | < 0.2 EU/μg, determined by LAL method. |
| Storage | Lyophilized recombinant Human Adipolean/gArcp30 remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, Human Adipolean/gArcp30 should be stable up to 1 week at 4°C or up to 2 months at -20°C. |
| Note | For research use only |
ED₅₀< 2 μg/ml, measured in a cell proliferation assay using M1 cells.
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| Cat. No. Z03072 | ||
|---|---|---|
| Size | Price | |
| 10 ug | $65.00 | |
| 50 ug | $195.00 | |
| 1 mg | $2100.00 | |
