SARS-CoV-2 Spike protein (S1, N501Y, His Tag)

*This product has been discontinued!*

SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold to severe diseases. The spike protein mutation N501Y is one of six key contact residues within the receptor-binding domain (RBD) andhas been identified as increasing binding affinity to human and murine ACE2.

Cat. No.	Z03526
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Product Introduction Background Bottom Notes

Product Introduction

Species

SARS-CoV-2

Protein Construction

S1 protein [Gln14-Arg685 (N501Y)] Accession # P0DTC2	Poly-His
N-term	C-term

Purity

> 90% as analyzed by SDS-PAGE

Endotoxin Level

< 0.2 EU/μg of protein by gel clotting method

Biological Activity

SARS-CoV-2 Spike protein (S1, N501Y, His Tag) can bind with human ACE2 (Cat. No.: Z03484) in functional ELISA assay.

Expression System

293 Cells

Theoretical Molecular Weight

79 kDa

Formulation

Supplied as a solution in PBS pH 7.4

Concentration

Please refer to the COA for the specific lot.

Storage & Stability

Upon receiving, this product remains stable for up to 6 months at -20°C or below. Avoid repeated freeze-thaw cycles.

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Background

Target Background	SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold to severe diseases. The spike protein mutation N501Y is one of six key contact residues within the receptor-binding domain (RBD) andhas been identified as increasing binding affinity to human and murine ACE2.
Synonyms	SARS-CoV-2 S1 protein, N501Y; 2019-nCoV S1 protein, N501Y

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For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.