Catalog Products » SARS-CoV-2 Spike protein (RBD, Avi & His Tag)-HRP
SARS-CoV-2 Spike Protein (RBD, Avi & His Tag)-HRP

SARS-CoV-2 Spike protein (RBD, Avi & His tag)-HRP can bind with ACE-2 Fc Chimera, Human (Cat. No. Z03516) in a functional ELISA.

SARS-CoV-2 Spike protein (RBD, Avi & His Tag)-HRP

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus that causes coronavirus disease 2019 (COVID-19), the respiratory illness responsible for the COVID-19 pandemic. SARS-CoV-2 also known as 2019-nCoV, is a positive-sense single-stranded RNA virus and is believed to have zoonotic origins and has close genetic similarity to bat coronaviruses. The receptor binding domain (RBD) of spike protein of the SARS-CoV-2 virus binds Angiotensin-Converting Enzyme 2 (ACE2) to invade the host cells. Based on structural biology studies, the RBD can be oriented either in the up/standing or down/lying state with the up/standing state associated with higher pathogenicity.
Z03594
$110.00

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Product Introduction
Species SARS-CoV-2
Protein Construction
Spike RBD (Arg319-Ser591)
Accession # P0DTC2
Avi Poly-His
N-term C-term
Conjugate HRP
Biological Activity This protein is validated to bind with human ACE2 (Cat. No. Z03516) in functional ELISA assay.
Expression System Human Cells
Application The optimal dilution ratio should be determined by the end user for specific applications.
ELISA 1:1000
Formulation Supplied as a solution in PBS, pH 7.4, 0.1% ProClin 300.
Storage & Stability Upon receiving, this product remains stable for up to 3 months at 2-8°C. Protect from light.

Examples
  • SARS-CoV-2 Spike Protein (RBD, Avi & His Tag)-HRP
  • SARS-CoV-2 Spike Protein (RBD, Avi & His Tag)-HRP

    SARS-CoV-2 Spike protein (RBD, Avi & His tag)-HRP can bind with ACE-2 Fc Chimera, Human (Cat. No. Z03516) in a functional ELISA.


Background
Target Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus that causes coronavirus disease 2019 (COVID-19), the respiratory illness responsible for the COVID-19 pandemic. SARS-CoV-2 also known as 2019-nCoV, is a positive-sense single-stranded RNA virus and is believed to have zoonotic origins and has close genetic similarity to bat coronaviruses. The receptor binding domain (RBD) of spike protein of the SARS-CoV-2 virus binds Angiotensin-Converting Enzyme 2 (ACE2) to invade the host cells. Based on structural biology studies, the RBD can be oriented either in the up/standing or down/lying state with the up/standing state associated with higher pathogenicity.
Synonyms SARS-CoV-2 SP RBD, 2019-nCoV S1 RBD, SARS-CoV-2 S1 RBD
References 1. The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2. Nature Microbiology. 5 (4): 536–544. 
2. The proximal origin of SARS-CoV-2. Nature Medicine. 26 (4): 450–452. 
3. The Natural History, Pathobiology, and Clinical Manifestations of SARS-CoV-2 Infections. Journal of Neuroimmune Pharmacology. 15 (3): 359–386. 

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.


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