SARS-CoV-2 Spike protein (RBD, E484K, K417T, N501Y, Avi & His Tag)
| Species | SARS-CoV-2 | ||||||
| Protein Construction |
Expressed with the mutations of E484K, K417N, N501Y.
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| Purity | > 90% as analyzed by SDS-PAGE | ||||||
| Endotoxin Level | < 0.2 EU/μg of protein by gel clotting method | ||||||
| Biological Activity | SARS-CoV-2 Spike protein (RBD, E484K, K417T, N501Y, Avi & His Tag) can bind with human ACE2 in functional ELISA assay. | ||||||
| Expression System | CHO | ||||||
| Theoretical Molecular Weight | 33.7 kDa | ||||||
| Formulation | Supplied as a solution in PBS, pH 7.4. | ||||||
| Concentration | Please refer to the COA for the specific lot. | ||||||
| Storage & Stability | Upon receiving, this product remains stable for up to 6 months at -20°C or below. Please avoid repeated freeze-thaw cycles. |
Immobilized ACE-2 Fc Chimera, Human at 2 μg/mL can bind SARS-CoV-2 Spike protein (RBD, E484K, K417T, N501Y, Avi & His Tag) (Cat. No. Z03600) with a serial dilution.
THETM His Tag Antibody [HRP], mAb, Mouse(Cat.No.A00612) is used as a secondary antibody.
| Target Background | SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold to severe diseases. Lineage P.1, also known as the Brazil(ian) variant is one of the variants of SARS-CoV-2. This variant has 17 amino acid changes, ten of which are in its spike protein, including these three designated to be of particular concern: N501Y, E484K and K417T. SARS-CoV-2 Spike protein (RBD, E484K, K417T, N501Y, Avi & His Tag) carries a Avi Tag followed by a polyhistidine tag at the C-terminus. It has high binding affinity to human chimeric ACE2. |
| Synonyms | Lineage P.1; 20J/501Y.V3; VOC-202101/02; Brazil(ian) variant; Gamma variant |
| References |
1. Variants: distribution of cases data. GOV.UK. Retrieved 27 February 2021. 2. COVID-19: Virologist says Brazilian coronavirus variant detected in UK is not the one 'of concern'. 3. Genomic characterisation of an emergent SARS-CoV-2 lineage in Manaus: preliminary findings. |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
For more documents, please visit "Technical Support".
| Cat. No. Z03600 | ||
|---|---|---|
| Size | Price | |
| 100 μg | $380.00 | |
| 1 mg | $2100.00 | |
