Catalog Products » SARS-CoV-2 Spike protein S1, Omicron Variant, His Tag
SARS-CoV-2 Spike Protein S1, Omicron Variant, His Tag

Lane 1: 1 μg of SARS-CoV-2 Spike protein S1, Omicron Variant, His Tag (Cat. No. Z03729 ) (R)
Lane 2: 1 μg of SARS-CoV-2 Spike protein S1, Omicron Variant, His Tag (Cat. No. Z03729 ) (NR)
≥ 90% as analyzed by SDS-PAGE

SARS-CoV-2 Spike Protein S1, Omicron Variant, His Tag

Immobilized ACE-2 Fc Chimera, Human (Cat. No. Z03516) at 10 μg/mL can bind  SARS-CoV-2 Spike protein S1, Omicron Variant, His Tag (Cat. No. Z03729 ) with a serial dilution.
THE™ His Tag Antibody [HRP], mAb, Mouse (Cat.No.A00612) is used as a secondary antibody (0.2 μg/mL).   

SARS-CoV-2 Spike protein S1, Omicron Variant, His Tag

SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold to severe diseases. Recently, the new B.1.1.529 variant was confirmed in South Africa and preliminary evidence suggests an increased risk of reinfection with this variant. The B.1.1.529 variant was first reported to WHO on 24 November 2021 and WHO has designated this variant as a VOC (Variant of Concern), named Omicron. There are more than 30 mutations in the spike protein.
Z03729
$380.00

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Product Introduction
Species SARS-CoV-2
Protein Construction

Expressed with the mutations of A67V, del69-70, T95I, G142D, del143-145, del211, L212I, ins214EPE, G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H, T547K, D614G, H655Y, N679K, P681H.

S1 protein (Gln14-Arg685)
Accession # P0DTC2
Poly-His
N-term C-term
Purity ≥ 90% as analyzed by SDS-PAGE
Endotoxin Level ≤ 1 EU/μg of protein by gel clotting method
Biological Activity SARS-CoV-2 Spike protein S1, Omicron Variant, His Tag can bind with human ACE2 (Cat. No.: Z03516) in functional ELISA assay.
Expression System 293 Cells
Theoretical Molecular Weight 79 kDa
Apparent Molecular Weight ~117 kDa, on SDS-PAGE under reducing conditions.
Formulation Supplied as a solution in PBS pH 7.4
Concentration Please refer to the COA for the specific lot.
Storage & Stability Upon receiving, this product remains stable for up to 6 months at -20 °C or below. Avoid repeated freeze-thaw cycles.

Examples
  • SARS-CoV-2 Spike Protein S1, Omicron Variant, His Tag
  • SARS-CoV-2 Spike Protein S1, Omicron Variant, His Tag

    Lane 1: 1 μg of SARS-CoV-2 Spike protein S1, Omicron Variant, His Tag (Cat. No. Z03729 ) (R)
    Lane 2: 1 μg of SARS-CoV-2 Spike protein S1, Omicron Variant, His Tag (Cat. No. Z03729 ) (NR)
    ≥ 90% as analyzed by SDS-PAGE

  • SARS-CoV-2 Spike Protein S1, Omicron Variant, His Tag
  • SARS-CoV-2 Spike Protein S1, Omicron Variant, His Tag

    Immobilized ACE-2 Fc Chimera, Human (Cat. No. Z03516) at 10 μg/mL can bind  SARS-CoV-2 Spike protein S1, Omicron Variant, His Tag (Cat. No. Z03729 ) with a serial dilution.
    THE™ His Tag Antibody [HRP], mAb, Mouse (Cat.No.A00612) is used as a secondary antibody (0.2 μg/mL).   


Background
Target Background SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold to severe diseases. Recently, the new B.1.1.529 variant was confirmed in South Africa and preliminary evidence suggests an increased risk of reinfection with this variant. The B.1.1.529 variant was first reported to WHO on 24 November 2021 and WHO has designated this variant as a VOC (Variant of Concern), named Omicron. There are more than 30 mutations in the spike protein.
Synonyms B.1.1.529; Omicron variant
References 1. Classification of Omicron (B.1.1.529): SARS-CoV-2 Variant of Concern.
2. Omicron: What Is Known — and Still Unknown.  

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.


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