Catalog Products » TRAIL R4/TNFRSF10D[Biotin], His & Avi, Human

TRAIL R4/TNFRSF10D[Biotin], His & Avi, Human

TNF-related apoptosis inducing ligand (TRAIL) is a potential antitumor protein known for its ability to selectively eliminate various types of tumor cells without exerting toxic effects in normal cells and tissues. TRAIL-R2/DR5 as well as TRAIL-R3/DcR1 and TRAIL-R4/DcR2 were significantly higher expressed in advanced tumour stages.
Z04634
$660.00

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Product Introduction
Species Human
Protein Construction
TRAIL R4/TNFRSF10D (Ala56-His211)
Accession # Q9UBN6		 His Avi
N-term C-term
Conjugate Biotin
Purity > 95% as determined by Bis­Tris PAGE 
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Immobilized Human TRAIL, No Tag at 5μg/ml (100μl/well) on the plate can bind TRAIL R4/TNFRSF10D[Biotin], His & Avi, Human. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 19.4 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 38-50 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Background
Target Background TNF-related apoptosis inducing ligand (TRAIL) is a potential antitumor protein known for its ability to selectively eliminate various types of tumor cells without exerting toxic effects in normal cells and tissues. TRAIL-R2/DR5 as well as TRAIL-R3/DcR1 and TRAIL-R4/DcR2 were significantly higher expressed in advanced tumour stages.
Synonyms CD264; RSF10D; TRAILR4; DCR2; TRUNDD; TNFRSF10D

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.