Catalog Products » Transferrin R/CD71[Biotin], His & Avi, Human
Transferrin R/CD71[Biotin], His & Avi, Human

Immobilized Human Transferrin, His Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for Transferrin R/CD71[Biotin], His & Avi, Human, His Tag with the EC50 of 0.69 μg/ml determined by ELISA.

Transferrin R/CD71[Biotin], His & Avi, Human

Transferrin R/CD71[Biotin], His & Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Transferrin R/CD71[Biotin], His & Avi, Human

The transferrin receptor (CD71) is known as a receptor for IgA1 on mesangial cells. The transcript and protein expression of glomerular CD71 was determined by real-time polymerase chain reaction and immunohistochemistry. Human mesangial cells (HMCs) were treated with sera from IgAN patients and expression levels of CD71 and inflammatory cytokine markers were compared according to disease status.
Z04635
$660.00

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Product Introduction
Species Human
Protein Construction
Avi His Transferrin R/CD71 (Cys89-Phe760)
Accession # P02786
N-term C-term
Conjugate Biotin
Purity > 95% as determined by Bis-Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Immobilized Transferrin R/CD71[Biotin], His & Avi, Human at 0.5μg/ml (100μl/well) on the streptavidin precoated plate (5μg/ml) can bind Anti­Transferrin R Antibody, hFc Tag. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 77.9 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 80-85 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • Transferrin R/CD71[Biotin], His & Avi, Human
    • Transferrin R/CD71[Biotin], His & Avi, Human

    Immobilized Human Transferrin, His Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for Transferrin R/CD71[Biotin], His & Avi, Human, His Tag with the EC50 of 0.69 μg/ml determined by ELISA.

  • Transferrin R/CD71[Biotin], His & Avi, Human
    • Transferrin R/CD71[Biotin], His & Avi, Human

    Transferrin R/CD71[Biotin], His & Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background The transferrin receptor (CD71) is known as a receptor for IgA1 on mesangial cells. The transcript and protein expression of glomerular CD71 was determined by real-time polymerase chain reaction and immunohistochemistry. Human mesangial cells (HMCs) were treated with sera from IgAN patients and expression levels of CD71 and inflammatory cytokine markers were compared according to disease status.
Synonyms TR; TfR1; CD71; sTfR; T9; p90; TFRC; TFR

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.