Catalog Products » TNFSF15[Biotin], His & Avi, Mouse
TNFSF15[Biotin], His & Avi, Mouse

Immobilized Mouse DR3, His Tag at 1 μg/ml(100 μl/well) on the plate. Dose response curve for TNFSF15[Biotin], His & Avi, Mouse, His Tag with the EC50 of 21.4 ng/ml determined by ELISA.

TNFSF15[Biotin], His & Avi, Mouse

TNFSF15[Biotin], His & Avi, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 90%.

TNFSF15[Biotin], His & Avi, Mouse

TL1A and its functional receptor DR3 are members of the TNF/TNFR superfamilies of proteins.TL1A and DR3 are abundantly localized at inflamed intestinal areas of patients with IBD and mice with experimental ileitis or colitis and actively participate in the immunological pathways that underlie mucosal homeostasis and intestinal inflammation.Recently, an important role was demonstrated for TL1A/DR3 as potential mediators of intestinal fibrosis that is associated with the presence of gut inflammation.
Z04681
$660.00

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Product Introduction
Species Mouse
Protein Construction
Avi His TNFSF15 (Ala61-Leu252)
Accession # Q5UBV8
N-term C-term
Conjugate Biotin
Purity > 90% as determined by Bis-Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Immobilized Mouse DR3, His Tag at 1μg/ml (100μl/well) on the plate can bind TNFSF15[Biotin], His & Avi, Mouse. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 24.40 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 28-38 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • TNFSF15[Biotin], His & Avi, Mouse
    • TNFSF15[Biotin], His & Avi, Mouse

    Immobilized Mouse DR3, His Tag at 1 μg/ml(100 μl/well) on the plate. Dose response curve for TNFSF15[Biotin], His & Avi, Mouse, His Tag with the EC50 of 21.4 ng/ml determined by ELISA.

  • TNFSF15[Biotin], His & Avi, Mouse
    • TNFSF15[Biotin], His & Avi, Mouse

    TNFSF15[Biotin], His & Avi, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 90%.


Background
Target Background TL1A and its functional receptor DR3 are members of the TNF/TNFR superfamilies of proteins.TL1A and DR3 are abundantly localized at inflamed intestinal areas of patients with IBD and mice with experimental ileitis or colitis and actively participate in the immunological pathways that underlie mucosal homeostasis and intestinal inflammation.Recently, an important role was demonstrated for TL1A/DR3 as potential mediators of intestinal fibrosis that is associated with the presence of gut inflammation.
Synonyms TL1A; VEGI-251; TNFSF15; TL1; VEGI; VEGI192A

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.