Catalog Products » TIGIT, His, Cynomolgus/Rhesus macaque

TIGIT, His, Cynomolgus/Rhesus macaque

TIGIT, also called Vstm3, Vsig9, and WUCAM, is a transmembrane protein in the CD28 family of the Ig superfamily proteins.IGIT is expressed at low levels on peripheral memory and regulatory CD4 T-cells and NK cells and is up-regulated following activation of these cells.
Z04956
$340.00

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Product Introduction
Species Cynomolgus/Rhesus macaque
Protein Construction
TIGIT (Met22-Ile141)
Accession # XP_015300911.1		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Immobilized TIGIT, His, Cynomolgus/Rhesus macaque at 1μg/ml (100μl/Well) on the plate can bind Anti­TIGIT Antibody, hFc Tag. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 14.4 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 18-25 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Background
Target Background TIGIT, also called Vstm3, Vsig9, and WUCAM, is a transmembrane protein in the CD28 family of the Ig superfamily proteins.IGIT is expressed at low levels on peripheral memory and regulatory CD4 T-cells and NK cells and is up-regulated following activation of these cells.
Synonyms TIGIT; VSIG9; VSTM3; WUCAM

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.