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Oncogenic cholesterol rewires lipid metabolism in hepatocellular carcinoma via the CSNK2A1-IGF2R Ser2484 axis
Authors: Ren-Yi Su, Chen-Hao Xu, Hai-Jun Guo, Li-Jun Meng, Jian-Yong Zhuo, Nan Xu, Hui-Gang Li, Chi-Yu He, Xuan-Yu Zhang, Zheng-Xin Lian, Shuai Wang, Chenhao Cao, Ruhong Zhou, Di Lu, Shu-Sen Zheng, Xu-Yong Wei, Xiao Xu
Journal: J Adv Res
PubMed ID: 39547439
Doi: 10.1016/j.jare.2024.11.021
Identification of FBLL1 as a neuron-specific RNA 2'-O-methyltransferase mediating neuronal differentiation
Authors: Deyu Zhang , Bo Li , Henan Xu , Jingying Li , Chao Ma , Wei Ge , Congcong Lu , and Xuetao Cao
Journal: Proc Natl Acad Sci U S A
PubMed ID: 39570315
Doi: 10.1073/pnas.2406961121
Fused extracellular vesicles from M2 macrophages and human umbilical cord mesenchymal stem cells for the targeted regulation of macrophage pyroptosis in periprosthetic osteolysis
Authors: Qimeng Liu , Tianliang Ma , Zheyu Zhang , Jiangyu Nan , Guanzhi Liu , Yute Yang , Yihe Hu , Jie Xie
Journal: J Extracell Vesicles
PubMed ID: 39711510
Doi: 10.1002/jev2.70028
Split-design approach enhances the therapeutic efficacy of ligand-based CAR-T cells against multiple B-cell malignancies
Authors: Shuhong Li , Licai Shi , Lijun Zhao , Qiaoru Guo , Jun Li , Ze-Lin Liu , Zhi Guo , Yu J Cao
Journal: Nat Commun
PubMed ID: 39528513
Doi: 10.1038/s41467-024-54150-z
Products & Services: Recombinant Proteins   Gene Synthesis   
Evolutionary insights into the stereoselectivity of imine reductases based on ancestral sequence reconstruction
Authors: Xin-Xin Zhu, Wen-Qing Zheng, Zi-Wei Xia, Xin-Ru Chen, Tian Jin, Xu-Wei Ding, Fei-Fei Chen, Qi Chen, Jian-He Xu, Xu-Dong Kong, Gao-Wei Zheng
Journal: Nat Commun
PubMed ID: 39609402
Doi: 10.1038/s41467-024-54613-3
Products & Services: Gene Synthesis   
RAD18-catalysed formation of ubiquitination intermediate mimic of proliferating cell nuclear antigen PCNA
Authors: Liying Zhang, Zhiheng Deng, Yunxiang Du, Ziyu Xu, Tianyi Zhang, Zebin Tong, Huasong Ai, Lu-Jun Liang, Lei Liu
Journal: Bioorg Med Chem
PubMed ID: 39580855
Doi: 10.1016/j.bmc.2024.118016
A high-performance protein preparation approach in a single column-free step
Authors: Yuan Huang, Yuanyuan Zhang, Xiaofeng Yang, Zhanglin Lin
Journal: Trends Biotechnol
PubMed ID: 39537535
Doi: 10.1016/j.tibtech.2024.10.008
Spatial organization of PI3K-PI(3,4,5)P3-AKT signaling by focal adhesions
Authors: Jing Wang , Zhengyang An , Zhongsheng Wu , Wei Zhou , Pengyu Sun , Piyu Wu , Song Dang , Rui Xue , Xue Bai , Yongtao Du , Rongmei Chen , Wenxu Wang , Pei Huang , Sin Man Lam , Youwei Ai , Suling Liu , Guanghou Shui , Zhe Zhang , Zheng Liu , Jianyong Huang , Xiaohong Fang , Kangmin He
Journal: Mol Cell
PubMed ID: 39488211
Doi: 10.1016/j.molcel.2024.10.010
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Both chebulagic acid and punicalagin inhibit respiratory syncytial virus entry via multi-targeting glycoprotein and fusion protein
Authors: Yingcai Xiong , Keyu Tao , Tao Li , Yinghui Zhou , Zhaowei Zhang , Weiying Ou , Zhao Wang , Shouchuan Wang , Yayi Hou , Peng Cao , Jianjian Ji
Journal: J Virol
PubMed ID: 39508604
Doi: 10.1128/jvi.01536-24
Products & Services: Peptoid Synthesis   
Engineered mRNAs with stable structures minimize double-stranded RNA formation and increase protein expression
Authors: Qianshan Qin , Huayuan Yan , Weixiang Gao , Ruyin Cao , Guopeng Liu , Xiaojing Zhang , Niangang Wang , Wenjie Zuo , Lei Yuan , Peng Gao , Qi Liu
Journal: J Mol Biol
PubMed ID: 39427983
Doi: 10.1016/J.JMB.2024.168822
Products & Services: Gene Synthesis   
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