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Adeno-associated viral delivery of Env-specific antibodies prevents SIV rebound after discontinuing antiretroviral therapy
Authors: Vadim A Klenchin, Natasha M Clark, Nida K Keles, Saverio Capuano, Rosemarie Mason, Guangping Gao, Aimee Broman, Emek Kose, Taina T Immonen, Christine M Fennessey, Brandon F Keele, Jeffrey D Lifson, Mario Roederer, Matthew R Gardner, David T Evans
Journal: biorxiv
PubMed ID: 38895320
Doi: 10.1101/2024.05.30.593694
Products & Services: Codon Optimization   
Farnesyltransferase inhibitor lonafarnib suppresses respiratory syncytial virus infection by blocking conformational change of fusion glycoprotein
Authors: Qi Yang, Bao Xue, Fengjiang Liu, Yongzhi Lu, Jielin Tang, Mengrong Yan, Qiong Wu, Ruyi Chen, Anqi Zhou, Lijie Liu, Junjun Liu, Changbin Qu, Qingxin Wu, Muqing Fu, Jiayi Zhong, Jianwei Dong, Sijie Chen, Fan Wang, Yuan Zhou, Jie Zheng, Wei Peng, Jinsai Shang, Xinwen Chen
Journal: Signal Transduct Target Ther
PubMed ID: 38853183
Doi: 10.1038/s41392-024-01858-5
Products & Services: Catalog Peptides   
Microglia undergo sex-dimorphic transcriptional and metabolic rewiring during aging
Authors: Seokjo Kang, Emily Y Ko, Amelia E Andrews, Juliana E Shin, Karina J Nance, Pijus K Barman, Peter S Heeger, Willard M Freeman, Bérénice A Benayoun, Helen S Goodridge
Journal: J Neuroinflammation
PubMed ID: 38840206
Doi: 10.1186/s12974-024-03130-7
Library-Assisted Evolution in Eukaryotic Cells Yield Adenine Base Editors with Enhanced Editing Specificity
Authors: Shenlin Hsiao, Shuanghong Chen, Yanhong Jiang, Qiudao Wang, Yang Yang, Yongrong Lai, Tao Zhong, Jiaoyang Liao, Yuxuan Wu
Journal: Adv Sci (Weinh)
PubMed ID: 38874509
Doi: 10.1002/advs.202309004
Products & Services: Molecular Biology Reagents   
Discovery of RXFP2 genetic association in resistant hypertensive men and RXFP2 antagonists for the treatment of resistant hypertension
Authors: Shan-Shan Zhang, Lance Larrabee, Andrew H Chang, Sapna Desai, Lisa Sloan, Xin Wang, Yixuan Wu, Nazia Parvez, Karen Amaratunga, Allison C Hartman, Abby Whitnall, Joseph Mason, Nicholas P Barton, Audrey Y Chu, Jonathan M Davitte, Adam J Csakai, Caitlin Vestal Tibbetts, Audrey E Tolbert, Heather O'Keefe, Jessie Polanco, Joseph Foley, Casey Kmett, Jonathan Kehler, Gabriela Kozejova, Feng Wang, Andrew P Mayer, Patrick Koenig, Davide Foletti, Steven J Pitts, Christine G Schnackenberg
Journal: Sci Rep
PubMed ID: 38851835
Doi: 10.1038/s41598-024-62804-7
Products & Services: Molecular Biology Reagents   
A phage nucleus-associated protein from the jumbophage Churi inhibits bacterial growth through protein translation interference
Authors: Wichanan Wannasrichan, Sucheewin Krobthong, Chase J Morgan, Emily G Armbruster, Milan Gerovac, Yodying Yingchutrakul, Patompon Wongtrakoongate, Jörg Vogel, Chanat Aonbangkhen, Poochit Nonejuie, Joe Pogliano, Vorrapon Chaikeeratisak
Journal: biorxiv
PubMed ID: 38915640
Doi: 10.1101/2024.06.15.599175
Products & Services: Molecular Biology Reagents   
The pigeon circovirus evolution, epidemiology and interaction with the host immune system under One Loft Race rearing conditions
Authors: Tomasz Stenzel, Daria Dziewulska, Ewa Łukaszuk, Joy M Custer, Matthew D De Koch, Simona Kraberger, Arvind Varsani
Journal: Sci Rep
PubMed ID: 38877168
Doi: 10.1038/s41598-024-64587-3
Products & Services: Gene Synthesis   
Cleaved TMEM106B forms amyloid aggregates in central and peripheral nervous systems
Authors: Mehtap Bacioglu, Manuel Schweighauser, Derrick Gray, Sofia Lövestam, Taxiarchis Katsinelos, Annelies Quaegebeur, John van Swieten, Zane Jaunmuktane, Stephen W. Davies, Sjors H. W. Scheres, Michel Goedert, Bernardino Ghetti, and Maria Grazia Spillantini
Journal: Acta Neuropathologica
PubMed ID: 38886865
Doi: 10.1186/s40478-024-01813-z
A new anti-CRISPR gene promotes the spread of drug-resistance plasmids in Klebsiella pneumoniae
Authors: Chunyu Jiang, Chengzhi Yu, Shuyi Sun, Jiajia Lin, Mufeng Cai, Zhenquan Wei, Lingling Feng, Jianhui Li, Yan Zhang, Ke Dong ... Show moreAuthor Notes
Journal: Nucleic Acids Res
PubMed ID: 38888121
Doi: 10.1093/nar/gkae516
Structural basis for an early stage of the photosystem II repair cycle in Chlamydomonas reinhardtii
Authors: Anjie Li, Tingting You, Xiaojie Pang, Yidi Wang, Lijin Tian, Xiaobo Li & Zhenfeng Liu
Journal: Nature Communications
PubMed ID: 38890314
Doi: 10.1038/s41467-024-49532-2
Products & Services: CRISPR RNAs/Cas9 Proteins(INACTIVE)   
Androgen-responsive FOXP4 is a target for endometrial carcinoma
Authors: Kayo Kayahashi, Mahadi Hasan, Anowara Khatun, Susumu Kohno, Jumpei Terakawa, Shin-Ichi Horike, Natsumi Toyoda, Ayumi Matsuoka, Takashi Iizuka, Takeshi Obata, Masanori Ono, Yasunari Mizumoto, Chiaki Takahashi, Hiroshi Fujiwara, Takiko Daikoku
Journal: Commun Biol
PubMed ID: 38890503
Doi: 10.1038/s42003-024-06433-w
Products & Services: Molecular Biology Reagents   
Development of GPC3-CAR-NK cells and optimization as a therapy for HCC
Authors: Bihui Cao, Qianqian Ni, Zhuxin Chen, Shuo Yang, Xinkui Zhang, Haotao Su, Zhenfeng Zhang, Qi Zhao, Xiaolan Zhu, Manting Liu
Journal: J Leukoc Biol
PubMed ID: 38922297
Doi: 10.1093/jleuko/qiae144
Products & Services: Molecular Biology Reagents   
Electrophysiological Impact of SARS-CoV-2 Envelope Protein in U251 Human Glioblastoma Cells: Possible Implications in Gliomagenesis?
Authors: Lorenzo Monarca, Francesco Ragonese, Andrea Biagini, Paola Sabbatini, Matteo Pacini, Alessandro Zucchi, Roberta Spaccapelo, Paola Ferrari, Andrea Nicolini, Bernard Fioretti
Journal: Int J Mol Sci
PubMed ID: 38928376
Doi: 10.3390/ijms25126669
Products & Services: Gene Synthesis   
Baculovirus surface display of a chimeric E-NS1 protein of YFV protects against YFV infection
Authors: Carla Tomatis, María Florencia Ferrer, Silvia Aquila, Pablo Daniel Thomas, Paula Nazarena Arrías, Leticia Ferrelli, Matías Pidre, Victor Romanowski, Eugenio Antonio Carrera Silva, Ricardo Martín Gómez
Journal: Vaccine
PubMed ID: 38852036
Doi: 10.1016/j.vaccine.2024.06.013
Products & Services: Immunoassay Development Services   
miR-520e and its promoter region DNA methylation as potential biomarkers in atherosclerosis
Authors: Mimi Mu, Gao Liu, Xiaoyu Ding, Lijun Xue, Dandan Li, Yunhua Zhu, Nan Zhang, Jia Wu, Junjun Wang
Journal: Biochem Cell Biol
PubMed ID: 38917487
Doi: 10.1139/bcb-2023-0326
Products & Services: Molecular Biology Reagents   
Scaffold-enabled high-resolution cryo-EM structure determination of RNA
Authors: Daniel B Haack, Boris Rudolfs, Shouhong Jin, Kevin M Weeks, Navtej Toor
Journal: biorxiv
PubMed ID: 38915706
Doi: 10.1101/2024.06.10.598011
Products & Services: Molecular Biology Reagents   
Transgenic Soybean for Production of Thermostable α-Amylase
Authors: Zhenyan Cao, Ye Jiang, Jiajie Li, Ting Zheng, Chaoyang Lin, Zhicheng Shen
Journal: Plants (Basel)
PubMed ID: 38891347
Doi: 10.3390/plants13111539
Products & Services: Recombinant Proteins   
Enhancing precision targeting of ovarian cancer tumor cells in vivo through extracellular vesicle engineering
Authors: Mona Alharbi, Andrew Lai, Nihar Godbole, Dominic Guanzon, Soumyalekshmi Nair, Felipe Zuñiga, Alexander Quinn, Mengliu Yang, Sherry Y Wu, Carlos Salomon
Journal: Int J Cancer
PubMed ID: 38848494
Doi: 10.1002/ijc.35055
Products & Services: Molecular Biology Reagents   
Molecular determinants of olfactory receptor activation: Comparative analysis of Olfr205 and Olfr740 family member responses to indole
Authors: Guangyao Li, Li Wang, Fangzhou Ye, Shengju Li, Hongmeng Yu
Journal: Arch Biochem Biophys
PubMed ID: 38880319
Doi: 10.1016/j.abb.2024.110061
Products & Services: Molecular Biology Reagents   
Selenium nanoparticles enhance mucosal immunity against Mycobacterium bovis infection
Authors: Xin Ge, Zhengmin Liang, Kui Li, Yuhui Dong, Yuanzhi Wang, Yiduo Liu, ZiYi Liu, Haoran Wang, Yue Nan, SiYan Chen, Lin Li, Yanbin Guo, Xiangmei Zhou
Journal: Int Immunopharmacol
PubMed ID: 38878484
Doi: 10.1016/j.intimp.2024.112384
Products & Services: Molecular Biology Reagents   
Acetylation of the yeast Hsp40 chaperone protein Ydj1 fine-tunes proteostasis and translational fidelity
Authors: Siddhi Omkar, Courtney Shrader, Joel R Hoskins, Jake T Kline, Megan M Mitchem, Luca Fornelli, Sue Wickner, Andrew W Truman
Journal: biorxiv
PubMed ID: 38915721
Doi: 10.1101/2024.06.13.598777
Products & Services: Molecular Biology Reagents   
H3N2 canine influenza virus-like particle vaccine with great protection in beagle dogs
Authors: Fei-Fei Ge, Li-Pin Shen, De-Quan Yang, Xian-Cao Yang, Xin Li, Hai-Xiao Shen, Jian Wang, Shixin Huang
Journal: Microbiol Spectr
PubMed ID: 38874403
Doi: 10.1128/spectrum.00445-24
Products & Services: Gene Synthesis   
Identification of a novel glycoside hydrolase family 8 xylanase from Deinococcus geothermalis and its application at low temperatures
Authors: Tingting Wang, Min Lin, Yongliang Yan, Shijie Jiang, Qilin Dai, Zhengfu Zhou, Jin Wang
Journal: Arch Microbiol
PubMed ID: 38884653
Doi: 10.1007/s00203-024-04055-8
Prokaryotic RNA N1-Methyladenosine Erasers Maintain tRNA m1A Modification Levels in
Authors: Marcus Foo, Luke R Frietze, Behnam Enghiad, Yujie Yuan, Christopher D Katanski, Huimin Zhao, Tao Pan
Journal: ACS Chem Biol
PubMed ID: 38912606
Doi: 10.1021/acschembio.4c00278
Products & Services: Gene Synthesis   
Heterologous booster vaccination enhances antibody responses to SARS-CoV-2 by improving Tfh function and increasing B-cell clonotype SHM frequency
Authors: Yanli Song, Jiaolei Wang, Zhihui Yang, Changgui Li
Journal: Frontiers in Immunology
Doi: 10.3389/fimmu.2024.1406138
Products & Services: Catalog Peptides   
Tight Junction Component Occludin Binds to FIP5 to Regulate Endosome Trafficking and Mitotic Spindle Function
Authors: Zichao Zhang , Jing Chen , Rongze Ma , Chongshen Xu , Yunzhe Lu , Jiecan Zhou , Kun Xia , Pengfei Lu
Journal: Adv Sci (Weinh)
PubMed ID: 38884279
Doi: 10.1002/advs.202308822
Products & Services: Recombinant Proteins   
A bispecific antibody exhibits broad neutralization against SARS-CoV-2 Omicron variants XBB.1.16, BQ.1.1 and sarbecoviruses
Authors: Yingdan Wang # 1 2, Aihua Hao # 1, Ping Ji # 1, Yunping Ma # 1 3, Zhaoyong Zhang # 4, Jiali Chen 1, Qiyu Mao 1, Xinyi Xiong 4, Palizhati Rehati 1, Yajie Wang 1, Yanqun Wang 4, Yumei Wen 1, Lu Lu 1, Zhenguo Chen 1, Jincun Zhao 5 6, Fan Wu 7, Jinghe Huang 8 9, Lei Sun 10
Journal: Nat Commun
PubMed ID: 38879565
Doi: 10.1038/s41467-024-49096-1
Products & Services: Gene Synthesis   
The binding mechanism of an anti-multiple myeloma antibody to the human GPRC5D homodimer
Authors: Pengfei Yan , Xi Lin , Lijie Wu , Lu Xu , Fei Li , Junlin Liu , Fei Xu
Journal: Nat Commun
PubMed ID: 38898050
Doi: 10.1038/s41467-024-49625-y
Products & Services: Gene Synthesis   
Molecular recognition of the atypical chemokine-like peptide GPR15L by its cognate receptor GPR15
Authors: Zhongyuan Zhang , You Zheng , Lu Xu , Yang Yue , Kexin Xu , Fei Li 1, Fei Xu
Journal: Cell Discov
PubMed ID: 38918398
Doi: 10.1038/s41421-024-00698-5
Products & Services: Peptide Synthesis   
Epitope-specific antibody fragments block aggregation of AGelD187N, an aberrant peptide in gelsolin amyloidosis
Authors: Laura Leimu, Patrik Holm, Anna Gąciarz, Oskar Haavisto, Stuart Prince, Ullamari Pesonen, Tuomas Huovinen, Urpo Lamminmäki
Journal: J Biol Chem
PubMed ID: 38944121
Doi: 10.1016/j.jbc.2024.107507
PAM-flexible Engineered FnCas9 variants for robust and ultra-precise genome editing and diagnostics
Authors: Sundaram Acharya, Asgar Hussain Ansari, Prosad Kumar Das, Seiichi Hirano, Meghali Aich, Riya Rauthan, Sudipta Mahato, Savitri Maddileti, Sajal Sarkar, Manoj Kumar, Rhythm Phutela, Sneha Gulati, Abdul Rahman, Arushi Goel, C Afzal, Deepanjan Paul, Trupti Agrawal, Vinay Kumar Pulimamidi, Subhadra Jalali, Hiroshi Nishimasu, Indumathi Mariappan, Osamu Nureki, Souvik Maiti, Debojyoti Chakraborty
Journal: Nat Commun
PubMed ID: 38942756
Doi: 10.1038/s41467-024-49233-w
Products & Services: Gene Synthesis   
Experimental inoculation of pigs with monkeypox virus results in productive infection and transmission to sentinels
Authors: Emily Mantlo, Jessie D Trujillo, Natasha N Gaudreault, Igor Morozov, Charles E Lewis, Franco Matias-Ferreyra, Chester McDowell, Dashzeveg Bold, Taeyong Kwon, Konner Cool, Velmurugan Balaraman, Daniel Madden, Bianca Artiaga, Jayme Souza-Neto, Jeffrey B Doty, Mariano Carossino, Udeni Balasuriya, William C Wilson, Nikolaus Osterrieder, Lisa Hensley, Juergen A Richt
Journal: Emerg Microbes Infect
PubMed ID: 38712637
Doi: 10.1080/22221751.2024.2352434
Products & Services: PCR Cloning and Subcloning   
Effect of TIMPs and Their Minimally Engineered Variants in Blocking Invasion and Migration of Brain Cancer Cells
Authors: Elham Taheri, Maryam Raeeszadeh-Sarmazdeh
Journal: biorxiv
PubMed ID: 38895489
Doi: 10.1101/2024.06.05.597644
Products & Services: Catalog Peptides   
Arboviruses antagonize insect Toll antiviral immune signaling to facilitate the coexistence of viruses with their vectors
Authors: Dongsheng Jia, Guozhong Luo, Heran Guan, Tingting Yu, Xinyan Sun, Yu Du, Yiheng Wang, Hongyan Chen, Taiyun Wei
Journal: PLoS Pathog
PubMed ID: 38865374
Doi: 10.1371/journal.ppat.1012318
Products & Services: Polyclonal Antibody Services   
mRNA Vaccine for Alzheimer's Disease: Pilot Study
Authors: Armine Hovakimyan, Garri Chilingaryan, Olga King, Joia Kai Capocchi, Jean Paul Chadarevian, Hayk Davtyan, Roman Kniazev, Michael G Agadjanyan, Anahit Ghochikyan
Journal: Vaccines (Basel)
PubMed ID: 38932388
Doi: 10.3390/vaccines12060659
Products & Services: Catalog Peptides   
NbPTR1 confers resistance against Pseudomonas syringae pv actinidiae in kiwifruit
Authors: Shin-Mei Yeh, Minsoo Yoon, Sidney Scott, Abhishek Chatterjee, Lauren M Hemara, Ronan K Y Chen, Tianchi Wang, Kerry Templeton, Erik H A Rikkerink, Jay Jayaraman, Cyril Brendolise
Journal: Plant Cell Environ
PubMed ID: 38899426
Doi: 10.1111/pce.15002
Products & Services: Codon Optimization   
Double promoter and tandem gene strategy for efficiently expressing recombinant FGF21
Authors: Longying Liu, Nuoyi Ning, Simeng Xu, Dongqing Chen, Luping Zhou, Zhimou Guo, Xinmiao Liang, Xianlong Ye
Journal: Microb Cell Fact
PubMed ID: 38867280
Doi: 10.1186/s12934-024-02447-5
Products & Services: Gene Synthesis   
Discovery, characterization, and comparative analysis of new UGT72 and UGT84 family glycosyltransferases
Authors: Tuo Li, Annika J E Borg, Leo Krammer, Hansjörg Weber, Rolf Breinbauer, Bernd Nidetzky
Journal: Commun Chem
PubMed ID: 38942997
Doi: 10.1038/s42004-024-01231-1
Products & Services: Molecular Biology Reagents   
DNA mismatch and damage patterns revealed by single-molecule sequencing
Authors: Mei Hong Liu, Benjamin M Costa, Emilia C Bianchini, Una Choi, Rachel C Bandler, Emilie Lassen, Marta Grońska-Pęski, Adam Schwing, Zachary R Murphy, Daniel Rosenkjær, Shany Picciotto, Vanessa Bianchi, Lucie Stengs, Melissa Edwards, Nuno Miguel Nunes, Caitlin A Loh, Tina K Truong, Randall E Brand, Tomi Pastinen, J Richard Wagner, Anne-Bine Skytte, Uri Tabori, Jonathan E Shoag, Gilad D Evrony
Journal: Nature
PubMed ID: 38867045
Doi: 10.1038/s41586-024-07532-8
Products & Services: Molecular Biology Reagents   
IgE-Mediated Sensitization to Blo t 21 and Blo t 5 Is Associated With Asthma in the Tropics: A Case-Control Study
Authors: J Zakzuk, K Donado, E Mondol, V Marrugo, R Regino, J F López, K Hernandez, D Mercado, R Dennis, L Puerta, L Caraballo
Journal: J Investig Allergol Clin Immunol
PubMed ID: 38888580
Doi: 10.18176/jiaci.0892
Products & Services: Molecular Biology Reagents   
A soybean cyst nematode suppresses microbial plant symbionts using a lipochitooligosaccharide-hydrolysing enzyme
Authors: Wei Chen, Di Wang, Shaoyong Ke, Yangrong Cao, Wensheng Xiang, Xiaoli Guo, Qing Yang
Journal: Nat Microbiol
PubMed ID: 38886584
Doi: 10.1038/s41564-024-01727-5
Products & Services: Codon Optimization   
Structural Basis for Recognition of the FLAG-tag by Anti-FLAG M2
Authors: J Wouter Beugelink, Els Sweep, Bert J C Janssen, Joost Snijder, Matti F Pronker
Journal: J Mol Biol
PubMed ID: 38852931
Doi: 10.1016/j.jmb.2024.168649
Products & Services: Catalog Peptides   
Cost-Efficient Expression of Human Cardiac Myosin Heavy Chain in C2C12 Cells with a Non-Viral Transfection Reagent
Authors: Albin E Berg, Lok Priya Velayuthan, Alf Månsson, Marko Ušaj
Journal: Int J Mol Sci
PubMed ID: 38928453
Doi: 10.3390/ijms25126747
Products & Services: Molecular Biology Reagents   
CircVIRMA enhances cell malignant behavior by governing the miR-452-5p/CREBRF pathway in cervical cancer
Authors: Chengluo Hao, Jianjun Han, Kechao Xiang, Yun Wang, Xiangrui Chen, Chen Yang, Ailin Liang, Li Jia
Journal: Naunyn Schmiedebergs Arch Pharmacol
PubMed ID: 38850300
Doi: 10.1007/s00210-024-03159-8
Products & Services: Molecular Biology Reagents   
Circ_002033 Regulates Proliferation, Apoptosis, and Oxidative Damage of Bovine Mammary Epithelial Cells via the miR-199a-5p-MAP3K11 Axis in Heat Stress
Authors: Hanfang Zeng, Shujie Li, Haomiao Chang, Yunfei Zhai, Haihui Wang, Hantong Weng, Zhaoyu Han
Journal: J Agric Food Chem
PubMed ID: 38869955
Doi: 10.1021/acs.jafc.3c09835
Immune responses and reinfection of SARS-CoV-2 Omicron variant in patients with lung cancer
Authors: Chen Chen, Xiaoyun Zhou, Xiaoxing Gao, Ruili Pan, Qi He, Xiaobei Guo, Siyuan Yu, Na Wang, Qian Zhao, Mengzhao Wang, Yan Xu, Xiaohong Han
Journal: Int J Cancer
PubMed ID: 38837354
Doi: 10.1002/ijc.35038
Products & Services: Catalog Peptides   
Structure of the E. coli nucleoid-associated protein YejK reveals a novel DNA binding clamp
Authors: Maria A Schumacher, Rajiv R Singh, Raul Salinas
Journal: Nucleic Acids Res
PubMed ID: 38832628
Doi: 10.1093/nar/gkae459
Auxin resistant 2 and short hypocotyl 2 regulate cotton fiber initiation and elongation
Authors: Fei Jin, Liping Zhu, Liyong Hou, Hongbin Li, Ling Li, Guanghui Xiao
Journal: Plant Physiol
PubMed ID: 38527791
Doi: 10.1093/plphys/kiae183
Interleukin-1 beta (IL-1β) as adjuvant enhances the immune effects of Aeromonas veronii inactivated vaccine in largemouth bass (Micropterus salmoides)
Authors: Ze-Sheng Zhang, Heng-Chu Ren, Xie Gu, Qian-Rong Liang, Hui Fei, Yu-Hong Yang, Shun Yang, Liang-Yin He, Li-Li Liu
Journal: Int J Biol Macromol
PubMed ID: 38876231
Doi: 10.1016/j.ijbiomac.2024.133135
Products & Services: Molecular Biology Reagents   
Development of Broad-Spectrum Nanobodies for the Therapy and Diagnosis of SARS-CoV-2 and Its Multiple Variants
Authors: Lei He, Qian Wu, Zhaoyong Zhang, Lingling Chen, Kuai Yu, Leibin Li, Qiong Jia, Yanqun Wang, Jianqiang Ni, Chuanbin Wang, Qi Li, Xinyan Zhai, Jincun Zhao, Yuliang Liu, Ruiwen Fan, Yi-Ping Li
Journal: Mol Pharm
PubMed ID: 38920116
Doi: 10.1021/acs.molpharmaceut.4c00165
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