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Page: 7/1022 Results per page
PAM-flexible Engineered FnCas9 variants for robust and ultra-precise genome editing and diagnostics
Authors: Sundaram Acharya, Asgar Hussain Ansari, Prosad Kumar Das, Seiichi Hirano, Meghali Aich, Riya Rauthan, Sudipta Mahato, Savitri Maddileti, Sajal Sarkar, Manoj Kumar, Rhythm Phutela, Sneha Gulati, Abdul Rahman, Arushi Goel, C Afzal, Deepanjan Paul, Trupti Agrawal, Vinay Kumar Pulimamidi, Subhadra Jalali, Hiroshi Nishimasu, Indumathi Mariappan, Osamu Nureki, Souvik Maiti, Debojyoti Chakraborty
Journal: Nat Commun
PubMed ID: 38942756
Doi: 10.1038/s41467-024-49233-w
Products & Services: Gene Synthesis   
Experimental inoculation of pigs with monkeypox virus results in productive infection and transmission to sentinels
Authors: Emily Mantlo, Jessie D Trujillo, Natasha N Gaudreault, Igor Morozov, Charles E Lewis, Franco Matias-Ferreyra, Chester McDowell, Dashzeveg Bold, Taeyong Kwon, Konner Cool, Velmurugan Balaraman, Daniel Madden, Bianca Artiaga, Jayme Souza-Neto, Jeffrey B Doty, Mariano Carossino, Udeni Balasuriya, William C Wilson, Nikolaus Osterrieder, Lisa Hensley, Juergen A Richt
Journal: Emerg Microbes Infect
PubMed ID: 38712637
Doi: 10.1080/22221751.2024.2352434
Products & Services: PCR Cloning and Subcloning   
Effect of TIMPs and Their Minimally Engineered Variants in Blocking Invasion and Migration of Brain Cancer Cells
Authors: Elham Taheri, Maryam Raeeszadeh-Sarmazdeh
Journal: biorxiv
PubMed ID: 38895489
Doi: 10.1101/2024.06.05.597644
Products & Services: Catalog Peptides   
Arboviruses antagonize insect Toll antiviral immune signaling to facilitate the coexistence of viruses with their vectors
Authors: Dongsheng Jia, Guozhong Luo, Heran Guan, Tingting Yu, Xinyan Sun, Yu Du, Yiheng Wang, Hongyan Chen, Taiyun Wei
Journal: PLoS Pathog
PubMed ID: 38865374
Doi: 10.1371/journal.ppat.1012318
Products & Services: Polyclonal Antibody Services   
mRNA Vaccine for Alzheimer's Disease: Pilot Study
Authors: Armine Hovakimyan, Garri Chilingaryan, Olga King, Joia Kai Capocchi, Jean Paul Chadarevian, Hayk Davtyan, Roman Kniazev, Michael G Agadjanyan, Anahit Ghochikyan
Journal: Vaccines (Basel)
PubMed ID: 38932388
Doi: 10.3390/vaccines12060659
Products & Services: Catalog Peptides   
NbPTR1 confers resistance against Pseudomonas syringae pv actinidiae in kiwifruit
Authors: Shin-Mei Yeh, Minsoo Yoon, Sidney Scott, Abhishek Chatterjee, Lauren M Hemara, Ronan K Y Chen, Tianchi Wang, Kerry Templeton, Erik H A Rikkerink, Jay Jayaraman, Cyril Brendolise
Journal: Plant Cell Environ
PubMed ID: 38899426
Doi: 10.1111/pce.15002
Products & Services: Codon Optimization   
Double promoter and tandem gene strategy for efficiently expressing recombinant FGF21
Authors: Longying Liu, Nuoyi Ning, Simeng Xu, Dongqing Chen, Luping Zhou, Zhimou Guo, Xinmiao Liang, Xianlong Ye
Journal: Microb Cell Fact
PubMed ID: 38867280
Doi: 10.1186/s12934-024-02447-5
Products & Services: Gene Synthesis   
Discovery, characterization, and comparative analysis of new UGT72 and UGT84 family glycosyltransferases
Authors: Tuo Li, Annika J E Borg, Leo Krammer, Hansjörg Weber, Rolf Breinbauer, Bernd Nidetzky
Journal: Commun Chem
PubMed ID: 38942997
Doi: 10.1038/s42004-024-01231-1
Products & Services: Molecular Biology Reagents   
DNA mismatch and damage patterns revealed by single-molecule sequencing
Authors: Mei Hong Liu, Benjamin M Costa, Emilia C Bianchini, Una Choi, Rachel C Bandler, Emilie Lassen, Marta Grońska-Pęski, Adam Schwing, Zachary R Murphy, Daniel Rosenkjær, Shany Picciotto, Vanessa Bianchi, Lucie Stengs, Melissa Edwards, Nuno Miguel Nunes, Caitlin A Loh, Tina K Truong, Randall E Brand, Tomi Pastinen, J Richard Wagner, Anne-Bine Skytte, Uri Tabori, Jonathan E Shoag, Gilad D Evrony
Journal: Nature
PubMed ID: 38867045
Doi: 10.1038/s41586-024-07532-8
Products & Services: Molecular Biology Reagents   
IgE-Mediated Sensitization to Blo t 21 and Blo t 5 Is Associated With Asthma in the Tropics: A Case-Control Study
Authors: J Zakzuk, K Donado, E Mondol, V Marrugo, R Regino, J F López, K Hernandez, D Mercado, R Dennis, L Puerta, L Caraballo
Journal: J Investig Allergol Clin Immunol
PubMed ID: 38888580
Doi: 10.18176/jiaci.0892
Products & Services: Molecular Biology Reagents   
A soybean cyst nematode suppresses microbial plant symbionts using a lipochitooligosaccharide-hydrolysing enzyme
Authors: Wei Chen, Di Wang, Shaoyong Ke, Yangrong Cao, Wensheng Xiang, Xiaoli Guo, Qing Yang
Journal: Nat Microbiol
PubMed ID: 38886584
Doi: 10.1038/s41564-024-01727-5
Products & Services: Codon Optimization   
Structural Basis for Recognition of the FLAG-tag by Anti-FLAG M2
Authors: J Wouter Beugelink, Els Sweep, Bert J C Janssen, Joost Snijder, Matti F Pronker
Journal: J Mol Biol
PubMed ID: 38852931
Doi: 10.1016/j.jmb.2024.168649
Products & Services: Catalog Peptides   
Cost-Efficient Expression of Human Cardiac Myosin Heavy Chain in C2C12 Cells with a Non-Viral Transfection Reagent
Authors: Albin E Berg, Lok Priya Velayuthan, Alf Månsson, Marko Ušaj
Journal: Int J Mol Sci
PubMed ID: 38928453
Doi: 10.3390/ijms25126747
Products & Services: Molecular Biology Reagents   
CircVIRMA enhances cell malignant behavior by governing the miR-452-5p/CREBRF pathway in cervical cancer
Authors: Chengluo Hao, Jianjun Han, Kechao Xiang, Yun Wang, Xiangrui Chen, Chen Yang, Ailin Liang, Li Jia
Journal: Naunyn Schmiedebergs Arch Pharmacol
PubMed ID: 38850300
Doi: 10.1007/s00210-024-03159-8
Products & Services: Molecular Biology Reagents   
Circ_002033 Regulates Proliferation, Apoptosis, and Oxidative Damage of Bovine Mammary Epithelial Cells via the miR-199a-5p-MAP3K11 Axis in Heat Stress
Authors: Hanfang Zeng, Shujie Li, Haomiao Chang, Yunfei Zhai, Haihui Wang, Hantong Weng, Zhaoyu Han
Journal: J Agric Food Chem
PubMed ID: 38869955
Doi: 10.1021/acs.jafc.3c09835
Immune responses and reinfection of SARS-CoV-2 Omicron variant in patients with lung cancer
Authors: Chen Chen, Xiaoyun Zhou, Xiaoxing Gao, Ruili Pan, Qi He, Xiaobei Guo, Siyuan Yu, Na Wang, Qian Zhao, Mengzhao Wang, Yan Xu, Xiaohong Han
Journal: Int J Cancer
PubMed ID: 38837354
Doi: 10.1002/ijc.35038
Products & Services: Catalog Peptides   
Structure of the E. coli nucleoid-associated protein YejK reveals a novel DNA binding clamp
Authors: Maria A Schumacher, Rajiv R Singh, Raul Salinas
Journal: Nucleic Acids Res
PubMed ID: 38832628
Doi: 10.1093/nar/gkae459
Auxin resistant 2 and short hypocotyl 2 regulate cotton fiber initiation and elongation
Authors: Fei Jin, Liping Zhu, Liyong Hou, Hongbin Li, Ling Li, Guanghui Xiao
Journal: Plant Physiol
PubMed ID: 38527791
Doi: 10.1093/plphys/kiae183
Interleukin-1 beta (IL-1β) as adjuvant enhances the immune effects of Aeromonas veronii inactivated vaccine in largemouth bass (Micropterus salmoides)
Authors: Ze-Sheng Zhang, Heng-Chu Ren, Xie Gu, Qian-Rong Liang, Hui Fei, Yu-Hong Yang, Shun Yang, Liang-Yin He, Li-Li Liu
Journal: Int J Biol Macromol
PubMed ID: 38876231
Doi: 10.1016/j.ijbiomac.2024.133135
Products & Services: Molecular Biology Reagents   
Development of Broad-Spectrum Nanobodies for the Therapy and Diagnosis of SARS-CoV-2 and Its Multiple Variants
Authors: Lei He, Qian Wu, Zhaoyong Zhang, Lingling Chen, Kuai Yu, Leibin Li, Qiong Jia, Yanqun Wang, Jianqiang Ni, Chuanbin Wang, Qi Li, Xinyan Zhai, Jincun Zhao, Yuliang Liu, Ruiwen Fan, Yi-Ping Li
Journal: Mol Pharm
PubMed ID: 38920116
Doi: 10.1021/acs.molpharmaceut.4c00165
Synthetic Peptides Elicit Humoral Response against Porcine Reproductive and Respiratory Syndrome Virus in Swine
Authors: Francisco Perez-Duran, Fernando Calderon-Rico, Luis Enrique Franco-Correa, Alicia Gabriela Zamora-Aviles, Roberto Ortega-Flores, Daniel Durand-Herrera, Alejandro Bravo-Patiño, Ricarda Cortes-Vieyra, Ilane Hernandez-Morales, Rosa Elvira Nuñez-Anita
Journal: Vaccines (Basel)
PubMed ID: 38932381
Doi: 10.3390/vaccines12060652
Products & Services: Catalog Peptides   
Exploring a novel GH13_5 α-amylase from Jeotgalibacillus malaysiensis D5 for raw starch hydrolysis
Authors: Nurfatini Radzlin, Mohd Shukuri Mohamad Ali, Kian Mau Goh, Amira Suriaty Yaakop, Iffah Izzati Zakaria, Ummirul Mukminin Kahar
Journal: AMB Express
PubMed ID: 38874807
Doi: 10.1186/s13568-024-01722-3
Products & Services: Gene Synthesis   
Structural and mechanistic insights into a lysosomal membrane enzyme HGSNAT involved in Sanfilippo syndrome
Authors: Boyang Zhao, Zhongzheng Cao, Yi Zheng, Phuong Nguyen, Alisa Bowen, Robert H Edwards, Robert M Stroud, Yi Zhou, Menno Van Lookeren Campagne, Fei Li
Journal: Nat Commun
PubMed ID: 38918376
Doi: 10.1038/s41467-024-49614-1
Products & Services: PCR Cloning and Subcloning   
Development of a Ferritin Protein Nanoparticle Vaccine with PRRSV GP5 Protein
Authors: Xinjian Chang, Jun Ma, Yanrong Zhou, Shaobo Xiao, Xun Xiao, Liurong Fang
Journal: Viruses
PubMed ID: 38932282
Doi: 10.3390/v16060991
Products & Services: Molecular Biology Reagents   
Assessing Predictive Value of SARS-CoV-2 Epitope-Specific CD8 T-Cell Response in Patients with Severe Symptoms
Authors: Cristina Martín-Martín, Estefanía Salgado Del Riego, Jose R Vidal Castiñeira, Maria Soledad Zapico-Gonzalez, Mercedes Rodríguez-Pérez, Viviana Corte-Iglesias, Maria Laura Saiz, Paula Diaz-Bulnes, Dolores Escudero, Beatriz Suárez-Alvarez, Carlos López-Larrea
Journal: Vaccines (Basel)
PubMed ID: 38932408
Doi: 10.3390/vaccines12060679
Products & Services: Catalog Peptides   
Functional characterization of a cystatin A from the bat Myotis davidii
Authors: Gabriel Cerqueira Alves Costa, Ricardo Jose Soares Torquato, Vinícius de Morais Gomes, Lívia Rosa-Fernandes, Giuseppe Palmisano, Aparecida Sadae Tanaka
Journal: Comp Biochem Physiol B Biochem Mol Biol
PubMed ID: 38936799
Doi: 10.1016/j.cbpb.2024.111003
Products & Services: Custom Vector Construction   
C-terminal Poly-histidine Tags Alter Escherichia coli Polyphosphate Kinase Activity and Susceptibility to Inhibition
Authors: Marvin Q Bowlin, Avery D Lieber, Abagail R Long, Michael J Gray
Journal: J Mol Biol
PubMed ID: 38866092
Doi: 10.1016/j.jmb.2024.168651
Products & Services: Molecular Biology Reagents   
Production of norovirus-, rotavirus-, and enterovirus-like particles in insect cells is simplified by plasmid-based expression
Authors: Vili Lampinen, Stina Gröhn, Nina Lehmler, Minne Jartti, Vesa P Hytönen, Maren Schubert, Minna M Hankaniemi
Journal: Sci Rep
PubMed ID: 38937523
Doi: 10.1038/s41598-024-65316-6
Products & Services: Molecular Biology Reagents   
Red2Flpe-SCON: a versatile, multicolor strategy for generating mosaic conditional knockout mice
Authors: Szu-Hsien Sam Wu, Somi Kim, Heetak Lee, Ji-Hyun Lee, So-Yeon Park, Réka Bakonyi, Isaree Teriyapirom, Natalia Hallay, Sandra Pilat-Carotta, Hans-Christian Theussl, Jihoon Kim, Joo-Hyeon Lee, Benjamin D Simons, Jong Kyoung Kim, Gabriele Colozza, Bon-Kyoung Koo
Journal: Nat Commun
PubMed ID: 38862535
Doi: 10.1038/s41467-024-49382-y
Products & Services: Molecular Biology Reagents   
New wheat straw fermentation feed: recombinant efficient degradation of lignocellulose and increase feed protein
Authors: Xihua Chen, Xiaoyu Liang, Na Shi, Lu He, Yi Ma, Daochen Zhu, Zhong Ni, Huayou Chen
Journal: Prep Biochem Biotechnol
PubMed ID: 38824495
Doi: 10.1080/10826068.2024.2353637
Products & Services: Gene Synthesis   
Mechanism of human PINK1 activation at the TOM complex in a reconstituted system
Authors: Olawale G Raimi, Hina Ojha, Kenneth Ehses, Verena Dederer, Sven M Lange, Cristian Polo Rivera, Tom D Deegan, Yinchen Chen, Melanie Wightman, Rachel Toth, Karim P M Labib, Sebastian Mathea, Neil Ranson, Rubén Fernández-Busnadiego, Miratul M K Muqit
Journal: SCIENCE ADVANCES
PubMed ID: 38848361
Doi: 10.1126/sciadv.adn7191
Understanding the Phase Behavior of a Multistimuli-Responsive Elastin-like Polymer: Insights from Dynamic Light Scattering Analysis
Authors: Peter C Swanson, Galen P Arnold, Carolyn E Curley, Savannah C Wakita, Jeffery D V Waters, Eva Rose M Balog
Journal: J Phys Chem B
PubMed ID: 38830627
Doi: 10.1021/acs.jpcb.4c00070
Products & Services: Molecular Biology Reagents   
TnpB homologues exapted from transposons are RNA-guided transcription factors
Authors: Tanner Wiegand, Florian T Hoffmann, Matt W G Walker, Stephen Tang, Egill Richard, Hoang C Le, Chance Meers, Samuel H Sternberg
Journal: Nature
PubMed ID: 38926585
Doi: 10.1038/s41586-024-07598-4
Cholesterol neutralized vemurafenib treatment by promoting melanoma stem‑like cells via its metabolite 27‑hydroxycholesterol
Authors: Xiaohong Wang, Feiliang Zhong, Tingting Chen, Hongbo Wang, Weifang Wang, Hongkai Jin, Chouyang Li, Xuan Guo, Ying Liu, Yu Zhang, Bo Li
Journal: Cell Mol Life Sci
PubMed ID: 38775844
Doi: 10.1007/s00018-024-05267-3
Effect of Free Cysteine Residues to Serine Mutation on Cellodextrin Phosphorylase
Authors: Tomohiro Kuga, Naoki Sunagawa, Kiyohiko Igarashi
Journal: J Appl Glycosci (1999)
PubMed ID: 38863949
Doi: 10.5458/jag.jag.JAG-2023_0011
Products & Services: Molecular Biology Reagents   
Blue light-mediated gene expression as a promising strategy to reduce antibiotic resistance in Escherichia coli
Authors: Qingwei Jiang, Feng Geng, Juan Shen, Ping Zhu, Zhaoxin Lu, Fengxia Lu, Libang Zhou
Journal: Biotechnol J
PubMed ID: 38719589
Doi: 10.1002/biot.202400023
HIV-1 with gag processing defects activates cGAS sensing
Authors: Rebecca P Sumner, Henry Blest, Meiyin Lin, Carlos Maluquer de Motes, Greg J Towers
Journal: Retrovirology
PubMed ID: 38778414
Doi: 10.1186/s12977-024-00643-0
Products & Services: Molecular Biology Reagents   
Understanding the Enzyme ()-Norcoclaurine Synthase Promiscuity to Aldehydes and Ketones
Authors: Brunno A Salvatti, Marcelo A Chagas, Phillipe O Fernandes, Yan F X Ladeira, Aline S Bozzi, Veronica S Valadares, Ana Paula Valente, Amanda S de Miranda, Willian R Rocha, Vinicius G Maltarollo, Adolfo H Moraes
Journal: J Chem Inf Model
PubMed ID: 38776464
Doi: 10.1021/acs.jcim.3c01773
Products & Services: Molecular Biology Reagents   
Therapeutic potentials of nonpeptidic V2R agonists for partial cNDI-causing V2R mutants
Authors: Ritsuki Kuramoto, Ryoji Kise, Mayu Kanno, Kouki Kawakami, Tatsuya Ikuta, Noriko Makita, Asuka Inoue
Journal: PLoS ONE
PubMed ID: 38748623
Doi: 10.1371/journal.pone.0303507
Products & Services: Codon Optimization   
Micro-and nano-plastics induce kidney damage and suppression of innate immune function in zebrafish (Danio rerio) larvae
Authors: Hui Yang, Jian Ju, Yuting Wang, Zhu Zhu, Wenyan Lu, Yingying Zhang
Journal: Sci Total Environ
PubMed ID: 38703841
Doi: 10.1016/j.scitotenv.2024.172952
Products & Services: Catalog Antibody   
Preamplification-free ultra-fast and ultra-sensitive point-of-care testing via LwaCas13a
Authors: Wanting Zeng, Wanping Chen, Yang Liu, Ting Zhang, Chao Zhai, Wenqiang Li, Longyu Wang, Cheng Zhang, Qili Zeng, Fei Wang, Lixin Ma
Journal: Biosens Bioelectron
PubMed ID: 38776799
Doi: 10.1016/j.bios.2024.116400
Temperature-dependent iron motion in extremophile rubredoxins - no need for 'corresponding states'
Authors: Francis E Jenney, Hongxin Wang, Simon J George, Jin Xiong, Yisong Guo, Leland B Gee, Juan José Marizcurrena, Susana Castro-Sowinski, Anna Staskiewicz, Yoshitaka Yoda, Michael Y Hu, Kenji Tamasaku, Nobumoto Nagasawa, Lei Li, Hiroaki Matsuura, Tzanko Doukov, Stephen P Cramer
Journal: Sci Rep
PubMed ID: 38806591
Doi: 10.1038/s41598-024-62261-2
Tetrahydroxy stilbene glucoside rejuvenates aging hematopoietic stem cells with predilection for lymphoid differentiation via AMPK and Tet2
Authors: Dan Gao, Wei-Wei Yi, Bo Liu, Cong-En Zhang, Cui-Cui Yang, Li Zeng, Lin Li, Guangbin Luo, Lan Zhang, Zhen-Yu Ju, Jia-Bo Wang
Journal: J Adv Res
PubMed ID: 38704089
Doi: 10.1016/j.jare.2024.04.027
CRTAC1 identified as a promising diagnosis and prognostic biomarker in lung adenocarcinoma
Authors: Lin Tan, Han Zhang, Yun Ding, Yangyun Huang, Daqiang Sun
Journal: Sci Rep
PubMed ID: 38755183
Doi: 10.1038/s41598-024-61804-x
A RAB7A phosphoswitch coordinates Rubicon Homology protein regulation of Parkin-dependent mitophagy
Authors: Dan A Tudorica, Bishal Basak, Alexia S Puerta Cordova, Grace Khuu, Kevin Rose, Michael Lazarou, Erika L F Holzbaur, James H Hurley
Journal: J Cell Biol
PubMed ID: 38728007
Doi: 10.1083/jcb.202309015
Products & Services: Molecular Biology Reagents   
Antitumor activity of Z15-0-2, a bispecific nanobody targeting PD-1 and CTLA-4
Authors: Jianyao Zeng, Yuan Fang, Zixuan Zhang, Zhenzhen Lv, Xiaodie Wang, Qian Huang, Zhidan Tian, Jiaguo Li, Wenfeng Xu, Weimin Zhu, Jing Yu, Tao Liu, Qijun Qian
Journal: Oncogene
PubMed ID: 38806619
Doi: 10.1038/s41388-024-03066-5
Stacked mutations in wheat homologues of rice SEMI-DWARF1 confer a novel semi-dwarf phenotype
Authors: Barbora Ndreca, Alison Huttly, Sajida Bibi, Carlos Bayon, George Lund, Joshua Ham, Rocío Alarcón-Reverte, John Addy, Danuše Tarkowská, Stephen Pearce, Peter Hedden, Stephen G Thomas, Andrew L Phillips
Journal: BMC Plant Biol
PubMed ID: 38724935
Doi: 10.1186/s12870-024-05098-1
Products & Services: Mutant Libraries   
Acts as a Positive Regulator of Secondary Cell Wall Synthesis in Sudan Grass ( S)
Authors: Yanzhong Huang, Juanzi Wu, Jianyu Lin, Zhiwei Liu, Zhengfeng Mao, Chen Qian, Xiaoxian Zhong
Journal: Plants (Basel)
PubMed ID: 38794423
Doi: 10.3390/plants13101352
Products & Services: Gene Synthesis   
Development and validation of an HILIC/MS/MS method for determination of nusinersen in rabbit plasma
Authors: Xiao Zhang, Chunjie Sha, Wei Zhang, Fengjuan Zhao, Mingli Zhu, Guangyi Leng, Wanhui Liu
Journal: Heliyon
PubMed ID: 38799737
Doi: 10.1016/j.heliyon.2024.e31213
Products & Services: Gene Synthesis   
Identification and characterization of calcium binding protein, spermatid-associated 1 (CABS1)# in selected human tissues and fluids
Authors: Eduardo Reyes-Serratos, Joy Ramielle L Santos, Lakshmi Puttagunta, Stephen J Lewis, Mechiko Watanabe, Aron Gonshor, Robert Buck, A Dean Befus, Marcelo Marcet-Palacios
Journal: PLoS ONE
PubMed ID: 38753592
Doi: 10.1371/journal.pone.0301855
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