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Exploring bifunctional molecules for anti-SARS-CoV-2 and anti-inflammatory activity through structure-based virtual screening, SAR investigation, and biological evaluation
Authors: Jiani Lu , Yingying He , Yaqi Li , Xixiang Chen , Hongtao Li , Xuwen Chen , Jianrong Xu , Hongzhuan Chen ，Ying Wang , Xiao He , Shunying Liu , Lili Chen
Journal: Int J Biol Macromol
PubMed ID: 39653224
Doi: 10.1016/j.ijbiomac.2024.138529
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Mechanistic study of SCOOPs recognition by MIK2–BAK1 complex reveals the role of N-glycans in plant ligand–receptor– coreceptor complex formation
Authors: Huimin Wu , Lihao Wan , Zunyong Liu , Yunqing Jian , Chenchen Zhang , Xiakun Mao , Zhiyun Wang , Qiang Wang , Yaxin Hu , Lizhong Xiong , Zhujun Xia , Juan Xue , Shan Li , Ping He , Libo Shan , Shutong Xu
Journal: Nat Plants
PubMed ID: 39511418
Doi: 10.1038/s41477-024-01836-3
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Immunoaffinity Intact Top-Down Mass Spectrometry for Quantification of Neuron-Specific Enolase Gamma, a Low-Abundance Protein Biomarker
Authors: Sebastian A H van den Wildenberg , Sylvia A A M Genet , Maarten A C Broeren , Joost L J van Dongen , Maxime C M van den Oetelaar , Luc Brunsveld , Volkher Scharnhorst , Daan van de Kerkhof
Journal: Anal Chem
PubMed ID: 39710932
Doi: 10.1021/acs.analchem.4c04677
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SARS-CoV-2 specific adaptations in N protein inhibit NF-κB activation and alter pathogenesis
Authors: Xiao Guo , Shimin Yang , Zeng Cai , Shunhua Zhu , Hongyun Wang , Qianyun Liu , Zhen Zhang , Jiangpeng Feng , Xianying Chen , Yingjian Li , Jikai Deng , Jiejie Liu , Jiali Li , Xue Tan , Zhiying Fu , Ke Xu , Li Zhou , Yu Chen
Journal: J Cell Biol
PubMed ID: 39680116
Doi: 10.1083/jcb.202404131
Products & Services: Proteins, Expression, Isolation and Analysis   
Respiratory syncytial virus glycoprotein G impedes CX3CR1-activation by CX3CL1 and monocyte function
Authors: Robert Meineke, Ayse Agac, Marie-Christin Knittler, Martin Ludlow, Albert D. M. E. Osterhaus & Guus F. Rimmelzwaan
Journal: npj viruses
Doi: doi.org/10.1038/s44298-024-00075-9
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An Oral Nanovaccine Secreted by Genetically Engineered and Ultrasound-Responsive Bacteria for Colon Cancer Immunotherapy
Authors: Jiexin Li, Ruiqi Yang, Yihang Yuan, He Ren, Chao Fang, Jonathan F Lovell, and Yumiao Zhang
Journal: ADV FUNCT MATER
Doi: 10.1002/adfm.202414994
Products & Services: Peptide Synthesis   Recombinant Proteins   
Molecular basis of lipid and ligand regulation of prostaglandin receptor DP2
Authors: Jiuyin Xu , Youwei Xu , Li Hou , Xinheng He , Yang Li , Jing Zhao , Xue Meng , James Jiqi Wang , Yanli Wu , Heng Zhang , Yunhai Li , Wen Hu , Qingning Yuan , Kai Wu , Xi Cheng , Yi Jiang , Yu Xia , H Eric Xu , Canrong Wu
Journal: Proc Natl Acad Sci U S A .
PubMed ID: 39665758
Doi: 10.1073/pnas.2403304121
Products & Services: Proteins, Expression, Isolation and Analysis   
An Integrated Whole-Process Repair System with Programmed Regulation of Healing Performance Facilitates Urethral Wound Restoration and Scarless Reconstruction
Authors: Wenzhuo Fang , Ying Wang , Kaile Zhang , Ming Yang , Meng Liu , Yangwang Jin , Xianjie Xiu , Yuhui Wang , Zhenwei Yu , Ranxing Yang , Qiang Fu
Journal: Adv Sci (Weinh)
PubMed ID: 39691071
Doi: 10.1002/advs.202409930
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An intracellular bacterial pathogen triggers RIG-I/ MDA5-dependent necroptosis
Authors: Hang Xu , Huili Li , Boguang Sun,, Li Sun
Journal: Current Research in Microbial Sciences
Doi: doi.org/10.1016/j.crmicr.2024.100318
Products & Services: Proteins, Expression, Isolation and Analysis   
Reduced cross-protective potential of Omicron compared to ancestral SARS-CoV-2 spike vaccines against potentially zoonotic coronaviruses.
Authors: Tyler M. Renner, Matthew Stuible, Brian Cass, Sylvie Perret, Julie Guimond, Simon Lord-Dufour, Michael J. McCluskie, Yves Durocher & Bassel Akache
Journal: npj Viruses
Doi: 10.1038/s44298-024-00067-9
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