Resources » Reference Databases » Citations Database

For each citation that was shared on social media (LinkedIn, Facebook, or Twitter) with the “@GenScript” tag, the author will be rewarded with a $10 Amazon gift card or 2,000 GS points.

Gastroparesis is associated with decreased FOXF1 and FOXF2 in humans， and loss of FOXF1 and FOXF2 results in gastroparesis in mice.

Neurogastroenterol. Motil.. 2019; 
HerringBrian Paul，HoggattApril M，GuptaAnita，WoJo
Products/Services Used Details Operation
PCR Cloning and Subcloning … 1:200, rabbit polyclonal antibody, 3164; Cell Signaling), or PGP9.5 (1:200, Rabbit polyclonal antibody A01398‐40; Genscript, Piscataway, NJ … anti‐sheep Alexa Fluor 647, Alexa Fluor 488 or Rhodamine‐X (1:1000; Jackson ImmunoResearch, Westgrove, PA, USA) as appropriate … Get A Quote

Abstract

The transcription factors FOXF1 and FOXF2 have been implicated in the development of the gastrointestinal tract but their role in adults or in gastrointestinal diseases is poorly understood. We have recently shown that expression of serum response factor (SRF)， a transcription factor whose activity is modulated by FOXF proteins， is decreased in the stomach muscularis of patients with gastroparesis. The aim of the current study was to determine whether FOXF expression is decreased in gastroparesis patients and whether loss of FOXF1 and/or FOXF2 from adult smooth muscle is sufficient to impair gastric emptying in mice.

Keywords

Article Link >

Most Popular Services

Homology-Directed Repair (HDR) Knock-in Templates
CRISPR Cas9 Single guide RNA (sgRNA) and Ribonucleoprotein (RNP)
Plasmid DNA Preparation Service
Mammalian CHO Expression Service