For each citation that was shared on social media (LinkedIn, Facebook, or Twitter) with the “@GenScript” tag, the author will be rewarded with a $10 Amazon gift card or 2,000 GS points.
Citations Search |
- biorxiv 2020-12;
SARS-CoV-2 RNA reverse-transcribed and integrated into the human genome
Products/Services Used | Details | |
---|---|---|
![]() |
… Virus-neutralization assays were performed using the above reference SARS-CoV-2 strain in Vero E6 cells or the cPASS SARS-CoV-2 Neutralization Antibody Detection Kit (GenScript, catalog #L00847) 9 . Statistical analysis … | |
AbstractProlonged SARS-CoV-2 RNA shedding and recurrence of PCR-positive tests have been widely reported in patients after recovery, yet these patients most commonly are non-infectious. Here we investigated the possibility that SARS-CoV-2 RNAs can be reverse-transcribed and integrated into the human genome and that transcription of the integrated sequences might account for PCR-positive tests. In support of this hypothesis, we found chimeric transcripts consisting of viral fused to cellular sequences in published data sets of SARS-CoV-2 infected cultured cells and primary cells of patients, consistent with the transcription of viral sequences integrated into the genome. To experimentally corroborate the possibility of ... More KeywordsMost Popular Services |