Benz-Neburase™ GMP, tag-free is a genetically engineered endonuclease from Serratia marcescens that cleaves all forms of DNA and RNA non-specifically under a broad range of conditions. Benz-NeburaseTM Nuclease is mostly utilized to remove residual DNA and RNA during production process of biological molecules of interest in biopharmaceutical manufacturing including but not limited to vaccine production, viral vector production, as well as in gene and cell therapy-related manufacturing. Benz-Neburase™ GMP, tag free (Cat. No. Z03708) is manufactured in compliance with ISO 9001 and ISO 13485 quality management system standards and with more stringent process controls and relatively complete document records. The high-purity nucleases are suitable and fulfill the requirements for applications from basic research to clinical settings.