Histone H2A Antibody, pAb, Rabbit

*This product has been discontinued!*

Histone H2A is the core component of the nucleosome. It is involved in nucleosome wrapping and compacting of DNA into chromatin, limiting DNA’s accessibility to the cellular machinery. Histones thereby play a central role in transcription regulation, DNA repair, replication, and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, called histone code, and nucleosome remodeling.GenScript Rabbit Anti-Histone H2A Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide corresponding to the residues near carboxyl terminal of human histone H2A protein (Swiss Prot: Q16777).

Cat. No.	A01173
Size	Buy in bulk

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Overview Properties Background

Overview

Specificity	GenScript Rabbit Anti-Histone H2A Polyclonal Antibody detects endogenous levels of human histone H2A protein. It is predicted to react with mouse and fruit fly according to sequence homology.
Host Species	Rabbit
Immunogen	Synthetic peptide (KLH-coupled) derived from the carboxyl terminal of human histone H2A (Swiss Prot: Q16777)
Species Reactivity	Human. This product has not yet been tested with other species.

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Properties

Concentration	0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide
Reconstitution	Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/ml.
Purification	Immunoaffinity chromatography

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Background

Target Background

Histone H2A is the core component of the nucleosome. It is involved in nucleosome wrapping and compacting of DNA into chromatin, limiting DNA’s accessibility to the cellular machinery. Histones thereby play a central role in transcription regulation, DNA repair, replication, and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, called histone code, and nucleosome remodeling.
GenScript Rabbit Anti-Histone H2A Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide corresponding to the residues near carboxyl terminal of human histone H2A protein (Swiss Prot: Q16777).

Synonyms

Rabbit anti-Histone 2A;

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