Cofilin Antibody, pAb, Rabbit

*This product has been discontinued!*

Cofilin belongs to the actin-binding protein ADF family and it contains 1 ADF-H domain. Cofilin controls reversible actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin at a 1:1 ratio. It is the major component of intranuclear and cytoplasmic actin rods. It is involved in the translocation of the actin-cofilin complex from cytoplasm to nucleus. This protein is widely distributed in various tissues.GenScript Rabbit Anti-Cofilin Polyclonal Antibody is developed in rabbit hosts using a KLH-coupled synthetic peptide from amino terminal of human cofilin protein (Swiss Prot: P23528).

Cat. No.	A01239
Size	Buy in bulk

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Overview Properties Background

Overview

Specificity	GenScript Rabbit Anti-Cofilin Polyclonal Antibody detects endogenous levels of human and mouse cofilin protein. It is predicted to react with cynomolgus monkey, sheep, pig, and rat cofilin protein according to sequence homology.
Host Species	Rabbit
Immunogen	Synthetic peptide (KLH-coupled) from amino terminal of human cofilin protein (Swiss Prot: P23528).
Species Reactivity	Human and mouse. This product has not yet been tested with other species.

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Properties

Concentration	0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide
Reconstitution	Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/ml.
Purification	Immunoaffinity chromatography

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Background

Target Background

Cofilin belongs to the actin-binding protein ADF family and it contains 1 ADF-H domain. Cofilin controls reversible actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin at a 1:1 ratio. It is the major component of intranuclear and cytoplasmic actin rods. It is involved in the translocation of the actin-cofilin complex from cytoplasm to nucleus. This protein is widely distributed in various tissues.
GenScript Rabbit Anti-Cofilin Polyclonal Antibody is developed in rabbit hosts using a KLH-coupled synthetic peptide from amino terminal of human cofilin protein (Swiss Prot: P23528).

Synonyms

Rabbit Anti-Cofilin pAb;

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