Caspase 10 Antibody, pAb, Rabbit

*This product has been discontinued!*

Caspase 10 belongs to the peptidase C14A family. It is involved in the caspase activation cascade and the execution of apoptosis. Caspase 10 is recruited to both Fas- and TNFR-1 receptors in a FADD-dependent manner. Caspase 10 may participate in the granzyme B apoptotic pathways. It cleaves and activates caspase-3, -4, -6, -7, -8, and -9. Four isoforms of caspase 10 (caspase 10a, 10b, 10c, and 10d) have been described to date. These isoforms all have the same prodomain but different mature large and small subdomains.GenScript Rabbit Anti-Caspase 10 Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide from residues 169-219 of human caspase 10 protein (Swiss Prot: Q92851).

Cat. No.	A01280
Size	Buy in bulk

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Overview Properties Background

Overview

Specificity	GenScript Rabbit Anti-Caspase 10 Polyclonal Antibody detects full-length human caspase 10 protein.
Host Species	Rabbit
Immunogen	KLH-coupled synthetic peptide from residues 169-219 of human caspase 10 protein (Swiss Prot: Q92851)
Species Reactivity	Human. This product has not yet been tested with other species.

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Properties

Concentration	0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide
Reconstitution	Reconstitute the lyophilized powder with deionized water (or equivalent) to an final concentration of 0.5 mg/ml.
Purification	Immunoaffinity chromatography

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Background

Target Background

Caspase 10 belongs to the peptidase C14A family. It is involved in the caspase activation cascade and the execution of apoptosis. Caspase 10 is recruited to both Fas- and TNFR-1 receptors in a FADD-dependent manner. Caspase 10 may participate in the granzyme B apoptotic pathways. It cleaves and activates caspase-3, -4, -6, -7, -8, and -9. Four isoforms of caspase 10 (caspase 10a, 10b, 10c, and 10d) have been described to date. These isoforms all have the same prodomain but different mature large and small subdomains.
GenScript Rabbit Anti-Caspase 10 Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide from residues 169-219 of human caspase 10 protein (Swiss Prot: Q92851).

Synonyms

Rabbit Anti Caspase 10 (N-terminal) Polyclonal Antibody;

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