COX IV Antibody, pAb, Rabbit

*This product has been discontinued!*

Cytochrome c oxidase (COX) is a terminal enzyme complex involved in the mitochondrial electron transport chain. It consists of 13 subunits and is localized at the inner mitochondrial membrane. One of the small subunits of COX IV is encoded by nuclear DNA while the 3 largest subunits forming the catalytic core are encoded by mitochondrial DNA. Deficiency in COX activity leads to a number of human diseases. The COX IV antibody can be used effectively as a mitochondrial loading control.GenScript Rabbit Anti-COX IV Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide from C-terminal of human COX IV. (Swiss Prot: P13073).

Cat. No.	A01402
Size	Buy in bulk

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Overview Properties Background

Overview

Specificity	GenScript Rabbit Anti-COX IV Polyclonal Antibody detects endogenous levels of human and mouse COX IV protein. It is predicted to react with rat according to sequence homology.
Host Species	Rabbit
Immunogen	KLH-coupled synthetic peptide from C-terminal of human COX IV (Swiss Prot: P13073).
Species Reactivity	Human and mouse. This product has not yet been tested with other species.

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Properties

Concentration	0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide
Reconstitution	Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/ml.
Purification	Immunoaffinity chromatography

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Background

Target Background

Cytochrome c oxidase (COX) is a terminal enzyme complex involved in the mitochondrial electron transport chain. It consists of 13 subunits and is localized at the inner mitochondrial membrane. One of the small subunits of COX IV is encoded by nuclear DNA while the 3 largest subunits forming the catalytic core are encoded by mitochondrial DNA. Deficiency in COX activity leads to a number of human diseases. The COX IV antibody can be used effectively as a mitochondrial loading control.

GenScript Rabbit Anti-COX IV Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide from C-terminal of human COX IV. (Swiss Prot: P13073).

Synonyms

Rabbit Anti-COX IV pAb;

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