Catalog Products » Antibodies » Primary Antibodies » Phospho-Specific Antibodies » antibody : Rabbit Anti-TrkA Polyclonal Antibody
Cat. No.
Name
Size   
Price
Selected
A01403-40
40 μg
$79 $47
TrkA Antibody, pAb, Rabbitcustom antibody production
TrkA Antibody, pAb, Rabbit
Full Name TrkA Antibody, pAb, Rabbit
Abbreviated name-1
Rabbit Anti-TrkA pAb;
Documents
TrkA Antibody, pAb, RabbitDocument-MSDS: 9854_20090526220932.PDF (PDF)
Figures
TrkA Antibody, pAb, Rabbit zoomTrkA Antibody, pAb, Rabbit
Description
TrkA is one member of Trk receptor tyrosine kinases family that consists of TrkA, TrkB, and TrkC. TrkA plays an important role in proliferation and maturation of the nervous system. TrkA phosphorylation at Tyr490 is required for Shc association and activation of the Ras-MAP kinase cascade. TrkA kinase activity depends on phosphorylation of residues Tyr674/675 within catalytic domain. TrkA signals growth arrest and differentiation of cells originating from the neural crest, and can serve as a prognostic marker in neuroblastomas.

GenScript Rabbit Anti-TrkA Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide within residues 350-400 of human TrkA (Swiss Prot: P04629).
Ig Subclass
Rabbit IgG
Storage
The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.
Specificity
GenScript Rabbit Anti-TrkA Polyclonal Antibody detects human TrkA protein. It is predicted to react with mouse and rat according to sequence homology.
Concentration
0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide
Immunogen
KLH-coupled synthetic peptide within residues 350-400 of human TrkA (Swiss Prot: P04629).
Purification Method
Immunoaffinity chromatography
Reconstitution
Reconstitute the lyophilized powder with deionized water (or equivalent) to an final concentration of 0.5 mg/ml.
Applications
Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
ELISA: 0.05-0.2 µg/ml
Western blot: 0.5-1 µg/ml
Other Applications: user-optimized
Conjugation
Unconjugated
Species Reactivity
Human. This product has not been tested with other species yet.
Host Species
Rabbit
Antigen Species
Human
Technical Manual
ELISA Protocol (pdf)
Western Blot Protocol (pdf)
FACS Protocol (pdf)
IHC Protocol (pdf)
IP Protocol (pdf)
Document-COA
1
Antibody Services: GenScript's custom antibody service guarantees 1:32,000 ELISA titer of final product or two ELISA positive clones with the help of our advanced antigen design tool.
2
Polyclonal antibody Services: GenScript's custom polyclonal antibody services start from $250. It comes with a 1:32,000 ELISA titer guarantee, thanks to our advanced antigen design tool.
3
Custom Monoclonal Antibody Services: GenScript's custom monoclonal antibody service guarantees two ELISA positive clones with the help of advanced hybridoma technology & experienced professional.