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SNAP25 Antibody, pAb, Rabbit

*This product has been discontinued!*
SNAP25 (Synaptosome-Associated Protein of 25 kDa) is a membrane bound, pre-synaptic nerve terminal protein that is involved in the molecular regulation of neurotransmitter release. It is part of the SNARE core complex containing SNAP25, VAMP2 and STX1A. SNAP25 plays an important role toward achieving synaptic function of specific neuronal systems and it associates with proteins involved in vesicle docking and membrane fusion. In addition, SNAP25 plays an essential role in synaptic vesicle fusion and exocytosis.GenScript Rabbit Anti-SNAP25 Polyclonal Antibody is developed in rabbit using Purified His-tagged human SNAP25 (Swiss Prot: Q5U0B5) full length recombinant protein.
A01445
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Overview
Specificity GenScript Rabbit Anti-SNAP25 Polyclonal Antibody detects endogenous levels of human, mouse, and rat SNAP25.
Positive Control: Hela, SH-SY5Y, mouse brain and rat brain.
Host Species Rabbit
Immunogen Purified His-tagged human SNAP25 (Swiss Prot: Q5U0B5) full length recombinant protein.
Species Reactivity Human, mouse, and rat. This product has not been tested for other species yet.
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Properties
Concentration 0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide
Reconstitution Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/ml.
Purification Immunoaffinity chromatography
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Background
Target Background SNAP25 (Synaptosome-Associated Protein of 25 kDa) is a membrane bound, pre-synaptic nerve terminal protein that is involved in the molecular regulation of neurotransmitter release. It is part of the SNARE core complex containing SNAP25, VAMP2 and STX1A. SNAP25 plays an important role toward achieving synaptic function of specific neuronal systems and it associates with proteins involved in vesicle docking and membrane fusion. In addition, SNAP25 plays an essential role in synaptic vesicle fusion and exocytosis.
GenScript Rabbit Anti-SNAP25 Polyclonal Antibody is developed in rabbit using Purified His-tagged human SNAP25 (Swiss Prot: Q5U0B5) full length recombinant protein.
Synonyms Synaptosomal Associated Protein 25 antibody;
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Citations
GeertsCornelia J, et al. Tomosyn associates with secretory vesicles in neurons through its N- and C-terminal domains. PLoS ONE. (2017-01)