NQO1 antibody, pAb, Rabbit

Quinone oxidoreductase 1 (NQO1) is a cytosolic flavoenzyme that catalyzes the two-electron reduction of a broad range of substrates. It is one member of the NAD(P)H dehydrogenase (quinone) family. NQO1 functions as an important part of cellular antioxidant defense by detoxifying quinones thus preventing the formation of reactive oxygen species. NQO1 can serve as a detoxification enzyme for it has the ability to reduce quinone substrates directly to their less toxic hydroquinone derivatives. NQO1 can also function as an antioxidant enzyme reducing ubiquinone and vitamin E quinone to their antioxidant forms. GenScript Rabbit Anti-NQO1 Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide from C-terminal of human NQO1 (Swiss Prot: P15559).