CDX2 antibody, pAb, Rabbit

*This product has been discontinued!*

CDX2 is an intestine specific transcription factor that is expressed early in intestinal development. This transcription factor may be involved in the regulation of proliferation and differentiation of intestinal epithelial cells. CDX2 protein is expressed in primary and metastatic colorectal carcinomas and has also been demonstrated in the intestinal metaplasia of the stomach and intestinal-type gastric cancer, while it is not expressed in the normal gastric mucosa. CDX2 is likely to be superior marker compared to CK20.GenScript CDX2 Antibody is developed in rabbit using a KLH-coupled synthetic peptide within residues 150-200 of human CDX2 (Swiss Prot: Q99626).

Cat. No.	A01604
Size	Buy in bulk

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Overview Properties Background

Overview

Specificity	GenScript CDX2 Antibody detects endogenous levels of human and mouse CDX2. Predicted to react with rat CDX2 protein according to sequence homology. Positive Control: Jurkat, HEK293, HT29
Host Species	Rabbit
Immunogen	KLH-coupled synthetic peptide within residues 150-200 of human CDX2 (Swiss Prot: Q99626)
Species Reactivity	Human and mouse

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Properties

Concentration	0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide
Reconstitution	Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/ml.
Purification	Immunoaffinity chromatography

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Background

Target Background

CDX2 is an intestine specific transcription factor that is expressed early in intestinal development. This transcription factor may be involved in the regulation of proliferation and differentiation of intestinal epithelial cells. CDX2 protein is expressed in primary and metastatic colorectal carcinomas and has also been demonstrated in the intestinal metaplasia of the stomach and intestinal-type gastric cancer, while it is not expressed in the normal gastric mucosa. CDX2 is likely to be superior marker compared to CK20.
GenScript CDX2 Antibody is developed in rabbit using a KLH-coupled synthetic peptide within residues 150-200 of human CDX2 (Swiss Prot: Q99626).

Synonyms

Caudal type homeo box 2 Antibody;

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