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CDX2 antibody, pAb, Rabbit

Cat. No.	Name	Size	Price
A01604-200	CDX2 antibody, pAb, Rabbit	200 μg(5x40μg)	$225
A01604-40	CDX2 antibody, pAb, Rabbit	40 μg	$50

Full Name

CDX2 antibody, pAb, Rabbit

Abbreviated name-1

Caudal type homeo box 2 Antibody;

Documents
Document-MSDS: 11687_20100115002616.PDF (PDF)
Figures
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Reference

Description

CDX2 is an intestine specific transcription factor that is expressed early in intestinal development. This transcription factor may be involved in the regulation of proliferation and differentiation of intestinal epithelial cells. CDX2 protein is expressed in primary and metastatic colorectal carcinomas and has also been demonstrated in the intestinal metaplasia of the stomach and intestinal-type gastric cancer, while it is not expressed in the normal gastric mucosa. CDX2 is likely to be superior marker compared to CK20.
GenScript CDX2 Antibody is developed in rabbit using a KLH-coupled synthetic peptide within residues 150-200 of human CDX2 (Swiss Prot: Q99626).

Ig Subclass

Rabbit IgG

Storage

The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.

Specificity

GenScript CDX2 Antibody detects endogenous levels of human and mouse CDX2. Predicted to react with rat CDX2 protein according to sequence homology.
Positive Control: Jurkat, HEK293, HT29

Concentration

0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide

Immunogen

KLH-coupled synthetic peptide within residues 150-200 of human CDX2 (Swiss Prot: Q99626)

Purification Method

Immunoaffinity chromatography

Reconstitution

Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/ml.

Predicted Band Size

33 KD

Observed Band Size

37 KD

Applications

Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Western blot: 0.5-1 µg/ml
Other Applications: user optimized

Conjugation

Unconjugated

Species Reactivity

Human and mouse

Host Species

Rabbit

Antigen Species

Human

Technical Manual

TM0589.pdf (PDF)
TM0590.pdf (PDF)
TM0591.pdf (PDF)
TM0592.pdf (PDF)
TM0593.pdf (PDF)


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