HS1 Antibody, pAb, Rabbit

*This product has been discontinued!*

HS1 also known as HCLS1, is a substrate of the antigen receptor-coupled tyrosine kinase. The phosphorylation of HS1 catalyzed by Syk and Lyn plays a crucial role in the translocation of the protein to the membrane and is involved in the cytoskeleton rearrangement triggered by thrombin in human platelets. HS1 has been implicated in the signal transduction pathways in B and T lymphocytes. It plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. It may also be involved in the regulation of gene expression.GenScript HS1 Antibody, pAb, Rabbit is developed in rabbit using a KLH-coupled synthetic peptide within residues 250-300 of human HS1 (Swiss Prot: P14317).

Cat. No.	A01630
Size	Buy in bulk

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Overview Properties Background

Overview

Specificity	GenScript HS1 Antibody, pAb, Rabbit detects endogenous levels of human HS1. Positive Control: Jurkat
Host Species	Rabbit
Immunogen	KLH-coupled synthetic peptide within residues 250-300 of human HS1 (Swiss Prot: P14317)
Species Reactivity	Human. Reactivity to other species is not tested yet.

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Properties

Concentration	0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide
Reconstitution	Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/ml.
Purification	Immunoaffinity chromatography

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Background

Target Background

HS1 also known as HCLS1, is a substrate of the antigen receptor-coupled tyrosine kinase. The phosphorylation of HS1 catalyzed by Syk and Lyn plays a crucial role in the translocation of the protein to the membrane and is involved in the cytoskeleton rearrangement triggered by thrombin in human platelets. HS1 has been implicated in the signal transduction pathways in B and T lymphocytes. It plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. It may also be involved in the regulation of gene expression.
GenScript HS1 Antibody, pAb, Rabbit is developed in rabbit using a KLH-coupled synthetic peptide within residues 250-300 of human HS1 (Swiss Prot: P14317).

Synonyms

p75 antibody, pAb, Rabbit;

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