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| $210.00 | |
| A02654-50 | |
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| Ask us a question | |
| Specificity | This product is specific to p-Rb (S780) |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human Rb around the phosphorylation site of S780 |
| Species Reactivity | Human |
| Conjugate | Unconjugated |
| Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product. | |||||||
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| Form | Liquid |
| Storage Buffer | Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| Storage Instructions | Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed. |
| Purification | Affinity-chromatography |
| Isotype | Rabbit IgG |
| Clonality | Monoclonal |
Western blot analysis of Retinoblastoma phosphorylation expression in Jurkat cell lysate treated with Alkaline Phosphatase. »
| Target Background | Tumor suppressor that is a key regulator of the G1/S transition of the cell cycle. The hypophosphorylated form binds transcription regulators of the E2F family, preventing transcription of E2F-responsive genes. |
| Synonyms | OSRC; RB; p105-Rb; pRb; RB1; pp110; Retinoblastoma 1; PPP1R130 |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
