Catalog Products » IFN alpha/beta receptor 1 Antibody, mAb, Rabbit
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IFN alpha/beta receptor 1 Antibody, mAb, Rabbit

Together with IFNAR2, forms the heterodimeric receptor for type I interferons (including interferons alpha, beta, epsilon, omega and kappa). Type I interferon binding activates the JAK-STAT signaling cascade, resulting in transcriptional activation or repression of interferon-regulated genes that encode the effectors of the interferon response.
$210.00
A02845-50

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Overview
Specificity This product is specific to IFN alpha/beta receptor 1
Host Species Rabbit
Immunogen A synthesized peptide derived from human IFN alpha/beta receptor 1
Species Reactivity Human
Conjugate Unconjugated
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Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
Immunoprecipitation (IP) 1:20-1:50
Flow Cytometry 1:20-1:100
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Properties
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal
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IFN Alpha/beta Receptor 1 Antibody, MAb, Rabbit

Western blot analysis of IFNAR1 expression in K562 cell lysate. »

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Background
Target Background Together with IFNAR2, forms the heterodimeric receptor for type I interferons (including interferons alpha, beta, epsilon, omega and kappa). Type I interferon binding activates the JAK-STAT signaling cascade, resulting in transcriptional activation or repression of interferon-regulated genes that encode the effectors of the interferon response.
Synonyms AVP; IFRC; IFNAR; IFNBR; IFN-alpha-REC;
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.