Catalog Products » p-STAT5A (Y694) Antibody, mAb, Rabbit
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p-STAT5A (Y694) Antibody, mAb, Rabbit

Stat5 is activated in response to a wide variety of ligands including IL-2, GM-CSF, growth hormone and prolactin. Phosphorylation at Tyr694 is obligatory for Stat5 activation. This phosphorylation is mediated by Src upon erythropoietin stimulation. Stat5 is constitutively active in some leukemic cell types.
$210.00
A02951-50

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Overview
Specificity This product is specific to p-STAT5A (Y694)
Host Species Rabbit
Immunogen A synthesized peptide derived from human p-STAT5A (Y694)
Species Reactivity Human; Mouse
Conjugate Unconjugated
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Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
Immunohistochemistry (IHC) 1:100-1:200
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Properties
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal
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P-STAT5A (Y694) Antibody, MAb, Rabbit

Western blot analysis of Phospho-Stat5 (Y694) expression in A431 cell lysate treated with EGF. »

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Background
Target Background Stat5 is activated in response to a wide variety of ligands including IL-2, GM-CSF, growth hormone and prolactin. Phosphorylation at Tyr694 is obligatory for Stat5 activation. This phosphorylation is mediated by Src upon erythropoietin stimulation. Stat5 is constitutively active in some leukemic cell types.
Synonyms Signal transducer and activator of transcription 5A; STAT5; STAT5A; STAT5B; Transcription factor STAT5A; Transcription factor STAT5B; MGF;
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.