Catalog Products » Tryptase 1 Antibody, mAb, Rabbit
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Tryptase 1 Antibody, mAb, Rabbit

Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates.
$210.00
A03099-50

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Overview
Specificity This product is specific to Tryptase 1
Host Species Rabbit
Immunogen A synthesized peptide derived from human Tryptase 1
Species Reactivity Human; Mouse; Rat
Conjugate Unconjugated
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Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
Immunohistochemistry (IHC) 1:100-1:200
Immunoprecipitation (IP) 1:20-1:50
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Properties
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal
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Tryptase 1 Antibody, MAb, Rabbit

Western blot analysis of Mast Cell Tryptase expression in Human tonsil lysate. »

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Background
Target Background Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates.
Synonyms TPS1; TPS2; TPSAB1; TPSB1; MCP 7 ; Mast cell protease 7; Tryptase alpha 1;
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.