Catalog Products » Cytokeratin 2e Antibody, mAb, Rabbit
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Cytokeratin 2e Antibody, mAb, Rabbit

Probably contributes to terminal cornification.Associated with keratinocyte activation, proliferation and keratinization.Required for maintenance of corneocytes and keratin filaments in suprabasal keratinocytes in the epidermis of the ear, potentially via moderation of expression and localization of keratins and their partner proteins.Plays a role in the establishment of the epidermal barrier on plantar skin.
$210.00
A03192-50

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Overview
Specificity This product is specific to Cytokeratin 2e
Host Species Rabbit
Immunogen A synthesized peptide derived from human Cytokeratin 2e
Species Reactivity Human
Conjugate Unconjugated
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Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
Immunohistochemistry (IHC) 1:100-1:200
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Properties
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal
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Cytokeratin 2e Antibody, MAb, Rabbit

Western blot analysis of Cytokeratin 2e expression in A431 cell lysate. »

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Background
Target Background Probably contributes to terminal cornification.Associated with keratinocyte activation, proliferation and keratinization.Required for maintenance of corneocytes and keratin filaments in suprabasal keratinocytes in the epidermis of the ear, potentially via moderation of expression and localization of keratins and their partner proteins.Plays a role in the establishment of the epidermal barrier on plantar skin.
Synonyms CK 2e; Cytokeratin-2e; Epithelial keratin-2e; K2e; Keratin type II cytoskeletal 2 epidermal; Keratin-2 epidermis; KRT2; KRT2A; KRT2E; Type-II keratin Kb2;
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.