Catalog Products » p-PLK1 (T20) Antibody, mAb, Rabbit
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p-PLK1 (T20) Antibody, mAb, Rabbit

Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of anaphase-promoting complex/cyclosome (APC/C) inhibitors, and the regulation of mitotic exit and cytokinesis.
$210.00
A03226-50

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Overview
Specificity This product is specific to p-PLK1 (T20)
Host Species Rabbit
Immunogen A synthesized peptide derived from human PLK1 around the phosphorylation site of T20
Species Reactivity Human
Conjugate Unconjugated
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Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
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Properties
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal
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P-PLK1 (T20) Antibody, MAb, Rabbit

Western blot analysis of Phospho-PLK1 (T210) expression in (1) HeLa cell lysate; (2) HeLa cell treated with nocodazole lysate. »

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Background
Target Background Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of anaphase-promoting complex/cyclosome (APC/C) inhibitors, and the regulation of mitotic exit and cytokinesis.
Synonyms Cell cycle regulated protein kinase; PLK 1; PLK; Polo like kinase 1 ; Serine/threonine protein kinase 13; Serine/threonine protein kinase PLK1; STPK 13;
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.