STAT4 Antibody, mAb, Rabbit
| $210.00 | |
| A03249-50 | |
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| Ask us a question | |
IVD Raw Materials
| $210.00 | |
| A03249-50 | |
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|
|
| Ask us a question | |
| Specificity | This product is specific to STAT4 |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human STAT4 |
| Species Reactivity | Human |
| Conjugate | Unconjugated |
| Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product. | |||||||||||||||
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| Form | Liquid |
| Storage Buffer | Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| Storage Instructions | Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed. |
| Purification | Affinity-chromatography |
| Isotype | Rabbit IgG |
| Clonality | Monoclonal |
All lanes use the STAT4 Antibody, mAb, Rabbit at 1:1K dilution for 1 hour at room temperature. »
| Target Background | Transcriptional regulator mainly expressed in hematopoietic cells that plays a critical role in cellular growth, differentiation and immune response .Plays a key role in the differentiation of T-helper 1 cells and the production of interferon-gamma.Participates also in multiple neutrophil functions including chemotaxis and production of the neutrophil extracellular traps (By similarity).After IL12 binding to its receptor IL12RB2, STAT4 interacts with the intracellular domain of IL12RB2 and becomes tyrosine phosphorylated. |
| Synonyms | Signal transducer and activator of transcription 4; Stat-4; Stat 4; |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.