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Haptoglobin Antibody, mAb, Rabbit

As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.
$210.00
A03557-50

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Overview
Specificity This product is specific to Haptoglobin
Host Species Rabbit
Immunogen A synthesized peptide derived from human Haptoglobin
Species Reactivity Human; Mouse; Rat
Conjugate Unconjugated
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Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
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Properties
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal
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Haptoglobin Antibody, MAb, Rabbit

Western blot analysis of Haptoglobin expression in human plasma lysate. »

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Background
Target Background As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.
Synonyms Binding peptide; Haptoglobin alpha chain; Haptoglobin beta chain; HP2ALPHA2; HPA1S; Zonulin;
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.