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| $210.00 | |
| A04033-50 | |
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| Specificity | This product is specific to p-BAD (S75) |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human BAD around the phosphorylation site of S75 |
| Species Reactivity | Human; Mouse; Rat |
| Conjugate | Unconjugated |
| Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product. | |||||||
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| Form | Liquid |
| Storage Buffer | Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| Storage Instructions | Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed. |
| Purification | Affinity-chromatography |
| Isotype | Rabbit IgG |
| Clonality | Monoclonal |
Western blot analysis of Phospho-Bad (S112) expression in (1) HeLa cell lysate; (2) HeLa cell treated with Calcyculin A lysate. »
| Target Background | Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. |
| Synonyms | BAD; BBC2; BBC6; BCL2L8; |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
