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TMEM43 Antibody, mAb, Rabbit

May have an important role in maintaining nuclear envelope structure by organizing protein complexes at the inner nuclear membrane. Required for retaining emerin at the inner nuclear membrane.Plays a role in the modulation of innate immune signaling through the cGAS-STING pathway by interacting with RNF26.
$210.00
A04116-50

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Overview
Specificity This product is specific to TMEM43
Host Species Rabbit
Immunogen A synthesized peptide derived from human TMEM43
Species Reactivity Human; Mouse; Rat
Conjugate Unconjugated
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Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
Immunohistochemistry (IHC) 1:100-1:200
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Properties
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal
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TMEM43 Antibody, MAb, Rabbit

Western blot analysis of TMEM43 expression in Jurkat cell lysate. »

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Background
Target Background May have an important role in maintaining nuclear envelope structure by organizing protein complexes at the inner nuclear membrane. Required for retaining emerin at the inner nuclear membrane.Plays a role in the modulation of innate immune signaling through the cGAS-STING pathway by interacting with RNF26.
Synonyms ARVC5; ARVD5; EDMD7; LUMA; Tmem43; Transmembrane protein 43;
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.