SMCHD1 Antibody, mAb, Rabbit

Non-canonical member of the structural maintenance of chromosomes (SMC) protein family that plays a key role in epigenetic silencing by regulating chromatin architecture.Promotes heterochromatin formation in both autosomes and chromosome X, probably by mediating the merge of chromatin compartments.Plays a key role in chromosome X inactivation in females by promoting the spreading of heterochromatin.

Price	$210.00
Cat. No.	A04301-50
Size	50 μl 100 μl Buy in bulk
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Overview Applications Properties Background Bottom Notes

Overview

Specificity	This product is specific to SMCHD1
Host Species	Rabbit
Immunogen	A synthesized peptide derived from human SMCHD1
Species Reactivity	Human
Conjugate	Unconjugated

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Applications

Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.

Application	Recommended Usage
Western Blot	1:1000-1:2000
Immunohistochemistry (IHC)	1:100-1:200

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Properties

Form	Liquid
Storage Buffer	Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions	Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification	Affinity-chromatography
Isotype	Rabbit IgG
Clonality	Monoclonal

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Western blot analysis of SMCHD1 expression in 293T cell lysate. »

Background

Target Background

Synonyms

BAMS; FSHD2; Smchd1;

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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.