Dip13 alpha Antibody, mAb, Rabbit

Multifunctional adapter protein that binds to various membrane receptors, nuclear factors and signaling proteins to regulate many processes, such as cell proliferation, immune response, endosomal trafficking and cell metabolism.Regulates signaling pathway leading to cell proliferation through interaction with RAB5A and subunits of the NuRD/MeCP1 complex.

Price	$210.00
Cat. No.	A04366-50
Size	50 μl 100 μl Buy in bulk
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Overview Applications Properties Background Bottom Notes

Overview

Specificity	This product is specific to Dip13 alpha
Host Species	Rabbit
Immunogen	A synthesized peptide derived from human Dip13 alpha
Species Reactivity	Human; Mouse; Rat
Conjugate	Unconjugated

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Applications

Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.

Application	Recommended Usage
Western Blot	1:1000-1:2000
Immunohistochemistry (IHC)	1:100-1:200
Immunocytochemistry/Immunofluorescence (ICC/IF)	1:50-1:200
Immunohistochemistry Frozen (IHF)	1:50-1:200

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Properties

Form	Liquid
Storage Buffer	Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions	Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification	Affinity-chromatography
Isotype	Rabbit IgG
Clonality	Monoclonal

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Western blot analysis of APPL expression in Hela cell lysate. »

Background

Target Background	Multifunctional adapter protein that binds to various membrane receptors, nuclear factors and signaling proteins to regulate many processes, such as cell proliferation, immune response, endosomal trafficking and cell metabolism.Regulates signaling pathway leading to cell proliferation through interaction with RAB5A and subunits of the NuRD/MeCP1 complex.
Synonyms	DIP13 alpha; DP13A; KIAA1428; APPL1; Dip13-alpha; Adapter protein containing PH domain; DCC-interacting protein 13-alpha;

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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.