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DISC1 Antibody, mAb, Rabbit

Involved in the regulation of multiple aspects of embryonic and adult neurogenesis.Required for neural progenitor proliferation in the ventrical/subventrical zone during embryonic brain development and in the adult dentate gyrus of the hippocampus.Participates in the Wnt-mediated neural progenitor proliferation as a positive regulator by modulating GSK3B activity and CTNNB1 abundance.
$210.00
A04416-50

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Overview
Specificity This product is specific to DISC1
Host Species Rabbit
Immunogen A synthesized peptide derived from human DISC1
Species Reactivity Human; Mouse; Rat
Conjugate Unconjugated
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Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
Immunohistochemistry (IHC) 1:100-1:200
Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50-1:200
Immunohistochemistry Frozen (IHF) 1:50-1:200
Immunoprecipitation (IP) 1:20-1:50
Flow Cytometry 1:20-1:100
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Properties
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal
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DISC1 Antibody, MAb, Rabbit

Western blot analysis of DISC1 expression in (1) HeLa cell lysate; (2) RAW264.7 cell lysate; (3) PC-12 cell lysate. »

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Background
Target Background Involved in the regulation of multiple aspects of embryonic and adult neurogenesis.Required for neural progenitor proliferation in the ventrical/subventrical zone during embryonic brain development and in the adult dentate gyrus of the hippocampus.Participates in the Wnt-mediated neural progenitor proliferation as a positive regulator by modulating GSK3B activity and CTNNB1 abundance.
Synonyms C1orf136; DISC1; KIAA0457; RP4-730B13.1; SCZD9;
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.